Pesquisa | BVS Integralidade em Saúde

1.

Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza.

Abbott, Timothy R; Dhamdhere, Girija; Liu, Yanxia; Lin, Xueqiu; Goudy, Laine; Zeng, Leiping; Chemparathy, Augustine; Chmura, Stephen; Heaton, Nicholas S; Debs, Robert; Pande, Tara; Endy, Drew; La Russa, Marie F; Lewis, David B; Qi, Lei S.

Cell ; 181(4): 865-876.e12, 2020 05 14.

Artigo em Inglês | MEDLINE | ID: mdl-32353252

2.

Definitive demonstration by synthesis of genome annotation completeness.

Jaschke, Paul R; Dotson, Gabrielle A; Hung, Kay S; Liu, Diane; Endy, Drew.

Proc Natl Acad Sci U S A ; 116(48): 24206-24213, 2019 11 26.

Artigo em Inglês | MEDLINE | ID: mdl-31719208

3.

Switches, switches, every where, in any drop we drink.

Bonnet, Jérôme; Endy, Drew.

Mol Cell ; 49(2): 232-3, 2013 Jan 24.

Artigo em Inglês | MEDLINE | ID: mdl-23352244

4.

Fail-safe genetic codes designed to intrinsically contain engineered organisms.

Calles, Jonathan; Justice, Isaac; Brinkley, Detravious; Garcia, Alexa; Endy, Drew.

Nucleic Acids Res ; 47(19): 10439-10451, 2019 11 04.

Artigo em Inglês | MEDLINE | ID: mdl-31511890

5.

Correction to 'Fail-safe genetic codes designed to intrinsically contain engineered organisms'.

Calles, Jonathan; Justice, Isaac; Brinkley, Detravious; Garcia, Alexa; Endy, Drew.

Nucleic Acids Res ; 50(2): 1199, 2022 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-34935957

6.

Measurements of translation initiation from all 64 codons in E. coli.

Hecht, Ariel; Glasgow, Jeff; Jaschke, Paul R; Bawazer, Lukmaan A; Munson, Matthew S; Cochran, Jennifer R; Endy, Drew; Salit, Marc.

Nucleic Acids Res ; 45(7): 3615-3626, 2017 04 20.

Artigo em Inglês | MEDLINE | ID: mdl-28334756

7.

Precise and reliable gene expression via standard transcription and translation initiation elements.

Mutalik, Vivek K; Guimaraes, Joao C; Cambray, Guillaume; Lam, Colin; Christoffersen, Marc Juul; Mai, Quynh-Anh; Tran, Andrew B; Paull, Morgan; Keasling, Jay D; Arkin, Adam P; Endy, Drew.

Nat Methods ; 10(4): 354-60, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23474465

8.

Quantitative estimation of activity and quality for collections of functional genetic elements.

Mutalik, Vivek K; Guimaraes, Joao C; Cambray, Guillaume; Mai, Quynh-Anh; Christoffersen, Marc Juul; Martin, Lance; Yu, Ayumi; Lam, Colin; Rodriguez, Cesar; Bennett, Gaymon; Keasling, Jay D; Endy, Drew; Arkin, Adam P.

Nat Methods ; 10(4): 347-53, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23474467

9.

Composability of regulatory sequences controlling transcription and translation in Escherichia coli.

Kosuri, Sriram; Goodman, Daniel B; Cambray, Guillaume; Mutalik, Vivek K; Gao, Yuan; Arkin, Adam P; Endy, Drew; Church, George M.

Proc Natl Acad Sci U S A ; 110(34): 14024-9, 2013 Aug 20.

Artigo em Inglês | MEDLINE | ID: mdl-23924614

10.

Measurement and modeling of intrinsic transcription terminators.

Cambray, Guillaume; Guimaraes, Joao C; Mutalik, Vivek K; Lam, Colin; Mai, Quynh-Anh; Thimmaiah, Tim; Carothers, James M; Arkin, Adam P; Endy, Drew.

Nucleic Acids Res ; 41(9): 5139-48, 2013 May.

Artigo em Inglês | MEDLINE | ID: mdl-23511967

11.

Rewritable digital data storage in live cells via engineered control of recombination directionality.

Bonnet, Jerome; Subsoontorn, Pakpoom; Endy, Drew.

Proc Natl Acad Sci U S A ; 109(23): 8884-9, 2012 Jun 05.

Artigo em Inglês | MEDLINE | ID: mdl-22615351

12.

Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range.

Thomson, Ty M; Benjamin, Kirsten R; Bush, Alan; Love, Tonya; Pincus, David; Resnekov, Orna; Yu, Richard C; Gordon, Andrew; Colman-Lerner, Alejandro; Endy, Drew; Brent, Roger.

Proc Natl Acad Sci U S A ; 108(50): 20265-70, 2011 Dec 13.

Artigo em Inglês | MEDLINE | ID: mdl-22114196

13.

Measurement and modeling of intrinsic transcription terminators.

Cambray, Guillaume; Guimaraes, Joao C; Mutalik, Vivek K; Lam, Colin; Mai, Quynh-Anh; Thimmaiah, Tim; Carothers, James M; Arkin, Adam P; Endy, Drew.

Nucleic Acids Res ; 44(14): 7006, 2016 08 19.

Artigo em Inglês | MEDLINE | ID: mdl-27131373

14.

Engineering tRNA abundances for synthetic cellular systems.

Maheshwari, Akshay J; Calles, Jonathan; Waterton, Sean K; Endy, Drew.

Nat Commun ; 14(1): 4594, 2023 07 31.

Artigo em Inglês | MEDLINE | ID: mdl-37524714

15.

Colloidal Physics Modeling Reveals How Per-Ribosome Productivity Increases with Growth Rate in Escherichia coli.

Maheshwari, Akshay J; Sunol, Alp M; Gonzalez, Emma; Endy, Drew; Zia, Roseanna N.

mBio ; 14(1): e0286522, 2023 02 28.

Artigo em Inglês | MEDLINE | ID: mdl-36537810

16.

Multicolor plate reader fluorescence calibration.

Beal, Jacob; Telmer, Cheryl A; Vignoni, Alejandro; Boada, Yadira; Baldwin, Geoff S; Hallett, Liam; Lee, Taeyang; Selvarajah, Vinoo; Billerbeck, Sonja; Brown, Bradley; Cai, Guo-Nan; Cai, Liang; Eisenstein, Edward; Kiga, Daisuke; Ross, David; Alperovich, Nina; Sprent, Noah; Thompson, Jaclyn; Young, Eric M; Endy, Drew; Haddock-Angelli, Traci.

Synth Biol (Oxf) ; 7(1): ysac010, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35949424

17.

Direct and indirect impacts of synthetic biology on biodiversity conservation.

Macfarlane, Nicholas B W; Adams, Jonathan; Bennett, Elizabeth L; Brooks, Thomas M; Delborne, Jason A; Eggermont, Hilde; Endy, Drew; Esvelt, Kevin M; Kolodziejczyk, Bartlomiej; Kuiken, Todd; Oliva, Maria Julia; Peña Moreno, Sonia; Slobodian, Lydia; Smith, Risa B; Thizy, Delphine; Tompkins, Daniel M; Wei, Wei; Redford, Kent H.

iScience ; 25(11): 105423, 2022 Nov 18.

Artigo em Inglês | MEDLINE | ID: mdl-36388962

18.

Foundations for engineering biology.

Endy, Drew.

Nature ; 438(7067): 449-53, 2005 Nov 24.

Artigo em Inglês | MEDLINE | ID: mdl-16306983

19.

Regulated cell-to-cell variation in a cell-fate decision system.

Colman-Lerner, Alejandro; Gordon, Andrew; Serra, Eduard; Chin, Tina; Resnekov, Orna; Endy, Drew; Pesce, C Gustavo; Brent, Roger.

Nature ; 437(7059): 699-706, 2005 Sep 29.

Artigo em Inglês | MEDLINE | ID: mdl-16170311

20.

Determination of cell fate selection during phage lambda infection.

St-Pierre, François; Endy, Drew.

Proc Natl Acad Sci U S A ; 105(52): 20705-10, 2008 Dec 30.

Artigo em Inglês | MEDLINE | ID: mdl-19098103

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Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza.

Definitive demonstration by synthesis of genome annotation completeness.

Switches, switches, every where, in any drop we drink.

Fail-safe genetic codes designed to intrinsically contain engineered organisms.

Correction to 'Fail-safe genetic codes designed to intrinsically contain engineered organisms'.

Measurements of translation initiation from all 64 codons in E. coli.

Precise and reliable gene expression via standard transcription and translation initiation elements.

Quantitative estimation of activity and quality for collections of functional genetic elements.

Composability of regulatory sequences controlling transcription and translation in Escherichia coli.

Measurement and modeling of intrinsic transcription terminators.

Rewritable digital data storage in live cells via engineered control of recombination directionality.

Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range.

Measurement and modeling of intrinsic transcription terminators.

Engineering tRNA abundances for synthetic cellular systems.

Colloidal Physics Modeling Reveals How Per-Ribosome Productivity Increases with Growth Rate in Escherichia coli.

Multicolor plate reader fluorescence calibration.

Direct and indirect impacts of synthetic biology on biodiversity conservation.

Foundations for engineering biology.

Regulated cell-to-cell variation in a cell-fate decision system.

Determination of cell fate selection during phage lambda infection.