Detalhe da pesquisa
1.
Functional evaluation of epilepsy-associated KCNT1 variants in multiple cellular systems reveals a predominant gain of function impact on channel properties.
Epilepsia
; 64(8): 2126-2136, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37177976
2.
Human Pluripotent Stem Cell-Derived Kidney Model for Nephrotoxicity Studies.
Drug Metab Dispos
; 46(11): 1703-1711, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30171163
3.
Searching for cognitive enhancement in the Morris water maze: better and worse performance in D-amino acid oxidase knockout (Dao(-/-)) mice.
Eur J Neurosci
; 43(7): 979-89, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26833794
4.
Small molecule screening in human induced pluripotent stem cell-derived terminal cell types.
J Biol Chem
; 289(8): 4562-70, 2014 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24362033
5.
d-amino acid oxidase knockout (Dao(-/-) ) mice show enhanced short-term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption.
Eur J Neurosci
; 41(9): 1167-79, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25816902
6.
Increased burst-firing of ventral tegmental area dopaminergic neurons in D-amino acid oxidase knockout mice in vivo.
Eur J Neurosci
; 40(7): 2999-3009, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25040393
7.
Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration.
Sci Rep
; 14(1): 2153, 2024 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38272949
8.
Investigation of SAMD1 ablation in mice.
Sci Rep
; 13(1): 3000, 2023 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36810619
9.
Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice.
Drug Metab Dispos
; 40(11): 2067-73, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22837388
10.
Characterizing the composition of iPSC derived cells from bulk transcriptomics data with CellMap.
Sci Rep
; 12(1): 17394, 2022 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36253414
11.
Engineering multicellular living systems-a Keystone Symposia report.
Ann N Y Acad Sci
; 1518(1): 183-195, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36177947
12.
Human inducible pluripotent stem cells: Realization of initial promise in drug discovery.
Cell Stem Cell
; 28(9): 1507-1515, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34478628
13.
Generation of mice with a conditional allele for transforming growth factor beta 1 gene.
Genesis
; 47(6): 423-31, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19415629
14.
Author Correction: Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration.
Sci Rep
; 14(1): 9346, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38654092
15.
Best Practices for Translational Disease Modeling Using Human iPSC-Derived Neurons.
Neuron
; 100(4): 783-797, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30465765
16.
Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice.
Cancer Res
; 62(22): 6362-6, 2002 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12438215
17.
The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells.
Sci Rep
; 5: 16821, 2015 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26581770
18.
Integrating human pluripotent stem cells into drug development.
Cell Stem Cell
; 12(6): 669-77, 2013 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23746976
19.
Comparative gene expression profiling in human-induced pluripotent stem cell--derived cardiocytes and human and cynomolgus heart tissue.
Toxicol Sci
; 131(1): 292-301, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22982684
20.
Genetically engineered mouse models in drug discovery research.
Methods Mol Biol
; 602: 37-54, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20012391