Detalhe da pesquisa
1.
Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex.
Mol Cell
; 49(1): 172-85, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23142078
2.
Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152.
Proc Natl Acad Sci U S A
; 110(50): E4849-57, 2013 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24277814
3.
A chrysin derivative suppresses skin cancer growth by inhibiting cyclin-dependent kinases.
J Biol Chem
; 288(36): 25924-25937, 2013 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23888052
4.
Feed-forward mechanism of converting biochemical cooperativity to mitotic processes at the kinetochore plate.
Proc Natl Acad Sci U S A
; 108(20): 8200-5, 2011 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21525413
5.
Regulation of microtubule-based microtubule nucleation by mammalian polo-like kinase 1.
Proc Natl Acad Sci U S A
; 108(28): 11446-51, 2011 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21690413
6.
Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 8): 1522-9, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23897475
7.
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase.
Proc Natl Acad Sci U S A
; 107(46): 19742-7, 2010 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21041660
8.
Identification of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4-one derivatives as inhibitors of the phosphatase SerB653 in Porphyromonas gingivalis, implicated in periodontitis.
Bioorg Med Chem Lett
; 22(5): 2084-8, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22326397
9.
A role for Plk1 phosphorylation of NudC in cytokinesis.
Dev Cell
; 5(1): 127-38, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12852857
10.
Normal cells, but not cancer cells, survive severe Plk1 depletion.
Mol Cell Biol
; 26(6): 2093-108, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16507989
11.
CCT chaperonin complex is required for the biogenesis of functional Plk1.
Mol Cell Biol
; 25(12): 4993-5010, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15923617
12.
Role of Plk2 (Snk) in mouse development and cell proliferation.
Mol Cell Biol
; 23(19): 6936-43, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12972611
13.
IGF-II induced by hepatitis B virus X protein regulates EMT via SUMO mediated loss of E-cadherin in mice.
Oncotarget
; 7(35): 56944-56957, 2016 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27486970
14.
The MAP kinase pathway is required for entry into mitosis and cell survival.
Oncogene
; 23(3): 763-76, 2004 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-14737111
15.
The serum-inducible protein kinase Snk is a G1 phase polo-like kinase that is inhibited by the calcium- and integrin-binding protein CIB.
Mol Cancer Res
; 1(5): 376-84, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12651910
16.
Polo-like kinase 1 in the life and death of cancer cells.
Cell Cycle
; 2(5): 424-5, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12963832
17.
Induction of G1 Arrest by SB265610 Involves Cyclin D3 Down-regulation and Suppression of CDK2 (Thr160) Phosphorylation.
Anticancer Res
; 35(6): 3235-43, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26026083
18.
Preclinical evaluation of bortezomib/dipyridamole novel combination as a potential therapeutic modality for hematologic malignancies.
Mol Oncol
; 9(1): 309-22, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25245324
19.
Synthesis and antitumor activity of natural compound aloe emodin derivatives.
Chem Biol Drug Des
; 85(5): 638-44, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25323822
20.
Plk1-targeted therapies in TP53- or RAS-mutated cancer.
Mutat Res Rev Mutat Res
; 761: 31-39, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24630986