Detalhe da pesquisa
1.
Phospholamban inhibits the cardiac calcium pump by interrupting an allosteric activation pathway.
J Biol Chem
; 300(5): 107267, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38583863
2.
A novel machine learning-based screening identifies statins as inhibitors of the calcium pump SERCA.
J Biol Chem
; 299(5): 104681, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37030504
3.
Functional Role of an Unusual Transmembrane Acidic Residue in the Calcium Pump Regulator Myoregulin.
Biochemistry
; 62(8): 1331-1336, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37014032
4.
Fluorescence lifetime imaging microscopy reveals sodium pump dimers in live cells.
J Biol Chem
; 298(5): 101865, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35339486
5.
Primitive Phospholamban- and Sarcolipin-like Peptides Inhibit the Sarcoplasmic Reticulum Calcium Pump SERCA.
Biochemistry
; 61(14): 1419-1430, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35771007
6.
Structural Basis for the Function of the C-Terminal Proton Release Pathway in the Calcium Pump.
Int J Mol Sci
; 22(7)2021 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33805255
7.
Multiscale Simulation Reveals Passive Proton Transport Through SERCA on the Microsecond Timescale.
Biophys J
; 119(5): 1033-1040, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814059
8.
Dynamics-Driven Allostery Underlies Ca2+-Mediated Release of SERCA Inhibition by Phospholamban.
Biophys J
; 119(9): 1917-1926, 2020 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33069270
9.
Interaction of a Sarcolipin Pentamer and Monomer with the Sarcoplasmic Reticulum Calcium Pump, SERCA.
Biophys J
; 118(2): 518-531, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31858977
10.
Conserved Luminal C-Terminal Domain Dynamically Controls Interdomain Communication in Sarcolipin.
J Chem Inf Model
; 60(8): 3985-3991, 2020 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32668157
11.
Atomistic Structure and Dynamics of the Ca2+-ATPase Bound to Phosphorylated Phospholamban.
Int J Mol Sci
; 21(19)2020 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33019581
12.
Linking Biochemical and Structural States of SERCA: Achievements, Challenges, and New Opportunities.
Int J Mol Sci
; 21(11)2020 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32532023
13.
The Phospholamban Pentamer Alters Function of the Sarcoplasmic Reticulum Calcium Pump SERCA.
Biophys J
; 116(4): 633-647, 2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30712785
14.
Structural basis for relief of phospholamban-mediated inhibition of the sarcoplasmic reticulum Ca2+-ATPase at saturating Ca2+ conditions.
J Biol Chem
; 293(32): 12405-12414, 2018 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29934304
15.
Site-directed spectroscopy of cardiac myosin-binding protein C reveals effects of phosphorylation on protein structural dynamics.
Proc Natl Acad Sci U S A
; 113(12): 3233-8, 2016 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908877
16.
Preexisting domain motions underlie protonation-dependent structural transitions of the P-type Ca2+-ATPase.
Phys Chem Chem Phys
; 19(15): 10153-10162, 2017 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28374038
17.
Sarcolipin Promotes Uncoupling of the SERCA Ca2+ Pump by Inducing a Structural Rearrangement in the Energy-Transduction Domain.
Biochemistry
; 55(44): 6083-6086, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27731980
18.
Atomic-level mechanisms for phospholamban regulation of the calcium pump.
Biophys J
; 108(7): 1697-1708, 2015 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25863061
19.
Atomistic Characterization of the First Step of Calcium Pump Activation Associated with Proton Countertransport.
Biochemistry
; 54(33): 5235-41, 2015 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26250140
20.
Microsecond Molecular Simulations Reveal a Transient Proton Pathway in the Calcium Pump.
J Am Chem Soc
; 137(22): 7055-8, 2015 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26028459