Assuntos
Antibacterianos/efeitos adversos , Cloranfenicol/efeitos adversos , Dermatite Alérgica de Contato/etiologia , Prurigo/etiologia , Administração Tópica , Idoso , Antibacterianos/administração & dosagem , Antibacterianos/uso terapêutico , Cloranfenicol/administração & dosagem , Cloranfenicol/uso terapêutico , Clobetasol/uso terapêutico , Dermatite Alérgica de Contato/tratamento farmacológico , Dermatite Alérgica de Contato/patologia , Dermatite Alérgica de Contato/prevenção & controle , Seguimentos , Glucocorticoides/uso terapêutico , Humanos , Masculino , Colagenase Microbiana/uso terapêutico , Pomadas , Testes do Emplastro , Prurigo/tratamento farmacológico , Prurigo/patologia , Prurigo/prevenção & controle , Resultado do Tratamento , Úlcera Varicosa/tratamento farmacológicoAssuntos
Acne Vulgar/tratamento farmacológico , Antibacterianos/efeitos adversos , Clindamicina/efeitos adversos , Dermatite Alérgica de Contato/diagnóstico , Fármacos Dermatológicos/efeitos adversos , Administração Cutânea , Antibacterianos/uso terapêutico , Clindamicina/uso terapêutico , Dermatite Alérgica de Contato/etiologia , Fármacos Dermatológicos/uso terapêutico , Diagnóstico Diferencial , Feminino , Humanos , Retinoides/efeitos adversos , Adulto JovemRESUMO
Proteus syndrome (PS) is a postnatal mosaic overgrowth disorder, progressive and disfiguring. It is clinically diagnosed according to the criteria reported by Biesecker et al. We describe the case of a 49-year-old woman who presented with a 10-year history of pauci-symptomatic infiltrating plaque lesions on the sole and lateral margin of the left foot, which had been diagnosed as a keloid. The patient had a positive history for advanced melanoma and a series of subtle clinical signs, such as asymmetric face, scoliosis, multiple lipomas on the trunk, linear verrucous epidermal nevi, and hyperpigmented macules with a mosaic distribution. Even if the clinical presentation was elusive, she had enough criteria to be diagnosed with PS. This case describes the first evidence, to the best of our knowledge, of pauci-symptomatic PS in adulthood, reports its rare association with advanced melanoma, and illustrates the importance of even minor cutaneous clinical signs, especially when atypical, in formulating the diagnosis of a complex cutaneous condition such as this.
RESUMO
Lichen striatus is an acquired, benign, linear inflammatory dermatosis characterized by a sudden skin eruption along Blaschko's lines that usually is not associated with specific etiologic agents. In most cases, it is a self-limited dermatosis, but may relapse. Topical steroids are its first-line therapy, but this treatment is not always effective. We describe the case of a 45-year-old woman affected by a lichen striatus on her right limb resistant to topical corticosteroid therapy. The patient was successfully treated with cyclosporine (4 mg/kg/die) for 4 weeks with no recurrence of the dermatitis during the subsequent 1-year follow-up period.