Detalhe da pesquisa
1.
Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation.
Immunity
; 43(3): 463-74, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26320659
2.
Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site.
Proc Natl Acad Sci U S A
; 118(9)2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33619102
3.
Eribulin Activates the cGAS-STING Pathway via the Cytoplasmic Accumulation of Mitochondrial DNA.
Mol Pharmacol
; 100(4): 309-318, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34312217
4.
Mammalian STT3A/B oligosaccharyltransferases segregate N-glycosylation at the translocon from lipid-linked oligosaccharide hydrolysis.
Proc Natl Acad Sci U S A
; 115(38): 9557-9562, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30181269
5.
DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice.
J Autoimmun
; 81: 13-23, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28325644
6.
Cellular metabolism of unnatural sialic acid precursors.
Glycoconj J
; 32(7): 515-29, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25957566
7.
The Microtubule Destabilizer Eribulin Synergizes with STING Agonists to Promote Antitumor Efficacy in Triple-Negative Breast Cancer Models.
Cancers (Basel)
; 14(23)2022 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36497445
8.
Yuanhuacine Is a Potent and Selective Inhibitor of the Basal-Like 2 Subtype of Triple Negative Breast Cancer with Immunogenic Potential.
Cancers (Basel)
; 13(11)2021 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34200174
9.
A bioactive mammalian disaccharide associated with autoimmunity activates STING-TBK1-dependent immune response.
Nat Commun
; 10(1): 2377, 2019 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31147550
10.
Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex.
Cell Rep
; 18(11): 2600-2607, 2017 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28297665