Detalhe da pesquisa
1.
New antibacterial agents: Hybrid bioisoster derivatives as potential E. coli FabH inhibitors.
Bioorg Med Chem Lett
; 26(16): 3988-93, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27426865
2.
A Review on Carbon Nanotubes Family of Nanomaterials and Their Health Field.
ACS Omega
; 9(8): 8687-8708, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38434894
3.
Design and exploratory data analysis of a second generation of dendrimer prodrugs potentially antichagasic and leishmanicide.
Mol Divers
; 17(4): 711-20, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23990201
4.
Drug/Lead Compound Hydroxymethylation as a Simple Approach to Enhance Pharmacodynamic and Pharmacokinetic Properties.
Front Chem
; 9: 734983, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35237565
5.
Design of Novel Phosphopantetheine Adenylyltransferase Inhibitors: A Potential New Approach to Tackle Mycobacterium tuberculosis.
Curr Top Med Chem
; 21(13): 1186-1197, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34323186
6.
3D-Pharmacophore mapping of thymidine-based inhibitors of TMPK as potential antituberculosis agents.
J Comput Aided Mol Des
; 24(2): 157-72, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20217185
7.
QSAR modeling of a set of pyrazinoate esters as antituberculosis prodrugs.
Arch Pharm (Weinheim)
; 343(2): 91-7, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20099263
8.
4D-QSAR: perspectives in drug design.
Molecules
; 15(5): 3281-94, 2010 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20657478
9.
Is prodrug design an approach to increase water solubility?
Int J Pharm
; 568: 118498, 2019 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31301465
10.
Antileishmanial activity screening of 5-nitro-2-heterocyclic benzylidene hydrazides.
Bioorg Med Chem
; 16(14): 6724-31, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18571927
11.
Structure-activity relationships for a class of selective inhibitors of the major cysteine protease from Trypanosoma cruzi.
J Enzyme Inhib Med Chem
; 23(6): 964-73, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19005945
12.
The latest advances in the discovery of nitric oxide hybrid drug compounds.
Expert Opin Drug Discov
; 12(9): 941-953, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28664751
13.
Design, synthesis and antitrypanosomal activity of some nitrofurazone 1,2,4-triazolic bioisosteric analogues.
Eur J Med Chem
; 121: 553-560, 2016 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27318979
14.
Rational design of new antituberculosis agents: receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives.
J Med Chem
; 47(15): 3755-64, 2004 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15239654
15.
Synthesis and in vitro evaluation of potential anti-leishmanial targeted drugs of pyrimethamine.
J Pharm Sci
; 92(10): 2109-16, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14502550
16.
Electrochemical evaluation of rhodium dimer-DNA interactions.
J Pharm Biomed Anal
; 29(4): 579-84, 2002 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12093486
17.
In vitro evaluation of verapamil and other modulating agents in Brazilian chloroquine-resistant Plasmodium falciparum isolates.
Rev Soc Bras Med Trop
; 36(1): 5-9, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12715057
18.
New tuberculostatic agents targeting nucleic acid biosynthesis: drug design using QSAR approaches.
Curr Pharm Des
; 20(27): 4474-85, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24245758
19.
Molecular modeling study on the disassembly of dendrimers designed as potential antichagasic and antileishmanial prodrugs.
J Mol Model
; 18(5): 2257-69, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21965079
20.
Molecular modeling and QSAR studies of a set of indole and benzimidazole derivatives as H4 receptor antagonists.
J Mol Model
; 17(5): 921-8, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20607332