Detalhe da pesquisa
1.
Pharmacology of a central nervous system delivered 2'-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates.
J Pharmacol Exp Ther
; 350(1): 46-55, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24784568
2.
Local and systemic tolerability of a 2'O-methoxyethyl antisense oligonucleotide targeting interleukin-4 receptor-α delivery by inhalation in mouse and monkey.
Inhal Toxicol
; 26(8): 452-63, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24932560
3.
A Semi-Mechanistic Population Pharmacokinetic Model of Nusinersen: An Antisense Oligonucleotide for the Treatment of Spinal Muscular Atrophy.
CPT Pharmacometrics Syst Pharmacol
; 7(9): 581-592, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30043511
4.
Control of terrestrial animal rabies in Anne Arundel County, Maryland, after oral vaccination of raccoons (1998-2007).
J Am Vet Med Assoc
; 241(6): 725-34, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22947155
5.
Renal uptake and tolerability of a 2'-O-methoxyethyl modified antisense oligonucleotide (ISIS 113715) in monkey.
Toxicology
; 301(1-3): 13-20, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22709826
6.
An in vivo approach to structure activity relationship analysis of peptide ligands.
Pharm Res
; 24(5): 868-79, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17377744