Detalhe da pesquisa
1.
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs.
Nature
; 605(7911): 741-746, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508656
2.
Pharmacokinetic drug-drug interaction study of the angiopoietin-1/angiopoietin-2-inhibiting peptibody trebananib (AMG 386) and paclitaxel in patients with advanced solid tumors.
Invest New Drugs
; 33(3): 691-9, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25895965
3.
Circadian variation in plasma 5-fluorouracil concentrations during a 24 hour constant-rate infusion.
BMC Cancer
; 15: 69, 2015 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25885822
4.
AMG 900, a potent inhibitor of aurora kinases causes pharmacodynamic changes in p-Histone H3 immunoreactivity in human tumor xenografts and proliferating mouse tissues.
J Transl Med
; 12: 307, 2014 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25367255
5.
Measurement of conatumumab-induced apoptotic activity in tumors by fine needle aspirate sampling.
Cytometry A
; 77(9): 849-60, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20623688
6.
A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours.
Oncotarget
; 5(22): 11154-67, 2014 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25525888
7.
Characterization of 64Cu-DOTA-conatumumab: a PET tracer for in vivo imaging of death receptor 5.
J Nucl Med
; 52(6): 942-9, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21571804
8.
A first-in-human study of conatumumab in adult patients with advanced solid tumors.
Clin Cancer Res
; 16(23): 5883-91, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20947515
9.
Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1.
J Clin Oncol
; 27(34): 5800-7, 2009 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19786654