Detalhe da pesquisa
1.
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2.
Proc Natl Acad Sci U S A
; 120(2): e2212931120, 2023 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36598939
2.
Closely related, yet unique: Distinct homo- and heterodimerization patterns of G protein coupled chemokine receptors and their fine-tuning by cholesterol.
PLoS Comput Biol
; 14(3): e1006062, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29529028
3.
Dynamic Cholesterol-Conditioned Dimerization of the G Protein Coupled Chemokine Receptor Type 4.
PLoS Comput Biol
; 12(11): e1005169, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27812115
4.
Docking for EP4R antagonists active against inflammatory pain.
Nat Commun
; 14(1): 8067, 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38057319
5.
Large library docking for novel SARS-CoV-2 main protease non-covalent and covalent inhibitors.
Protein Sci
; 32(8): e4712, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37354015
6.
The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature.
bioRxiv
; 2022 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35169801
7.
The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature.
Sci Adv
; 8(21): eabo5083, 2022 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35622909
8.
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 Macrodomain of SARS-CoV-2.
bioRxiv
; 2022 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35794891
9.
Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor.
Science
; 377(6614): eabn7065, 2022 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36173843
10.
A practical guide to large-scale docking.
Nat Protoc
; 16(10): 4799-4832, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34561691
11.
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Sci Adv
; 7(16)2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33853786
12.
Comprehensive Characterization of Lipid-Guided G Protein-Coupled Receptor Dimerization.
J Phys Chem B
; 124(14): 2823-2834, 2020 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32200641
13.
Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry.
Cell Rep
; 33(3): 108292, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33086068
14.
Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
bioRxiv
; 2020 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33269349
15.
Publisher Correction: A practical guide to large-scale docking.
Nat Protoc
; 17(1): 177, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34887579
16.
Membrane-Mediated Oligomerization of G Protein Coupled Receptors and Its Implications for GPCR Function.
Front Physiol
; 7: 494, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27826255