Detalhe da pesquisa
1.
Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator.
Biochem J
; 479(11): 1181-1204, 2022 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35552369
2.
CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins.
J Biol Chem
; 295(48): 16239-16250, 2020 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913128
3.
Molecular Mechanisms Underlying the Beneficial Effects of Exercise on Brain Function and Neurological Disorders.
Int J Mol Sci
; 22(8)2021 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33919972
4.
ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways.
FASEB J
; 33(12): 14825-14840, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31670977
5.
Functional analysis of an R311C variant of Ca2+ -calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder.
Bipolar Disord
; 22(8): 841-848, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32216002
6.
AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965.
J Biol Chem
; 293(23): 8874-8885, 2018 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29695504
7.
Allosteric regulation of AMP-activated protein kinase by adenylate nucleotides and small-molecule drugs.
Biochem Soc Trans
; 47(2): 733-741, 2019 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31000529
8.
Absence of the ß1 subunit of AMP-activated protein kinase reduces myofibroblast infiltration of the kidneys in early diabetes.
Int J Exp Pathol
; 100(2): 114-122, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31025787
9.
Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin.
J Am Soc Nephrol
; 29(9): 2326-2336, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29976587
10.
Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease.
J Neurosci
; 36(10): 3049-63, 2016 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26961958
11.
Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis.
Biochem J
; 469(2): 177-87, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25940306
12.
Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity.
Biochem J
; 461(2): 177-88, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24966052
13.
Activation of AMPK reduces the co-transporter activity of NKCC1.
Mol Membr Biol
; 31(2-3): 95-102, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24702155
14.
AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice.
Diabetologia
; 57(8): 1693-702, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24913514
15.
Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK.
Am J Physiol Renal Physiol
; 307(1): F96-F106, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24808538
16.
Significance of short chain fatty acid transport by members of the monocarboxylate transporter family (MCT).
Neurochem Res
; 37(11): 2562-8, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22878645
17.
Defective AMPK regulation of cholesterol metabolism accelerates atherosclerosis by promoting HSPC mobilization and myelopoiesis.
Mol Metab
; 61: 101514, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35562083
18.
An AMPKα2-specific phospho-switch controls lysosomal targeting for activation.
Cell Rep
; 38(7): 110365, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35172150
19.
Neuropeptide Y1 receptor antagonism protects ß-cells and improves glycemic control in type 2 diabetes.
Mol Metab
; 55: 101413, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34890851
20.
Blocking AMPK ß1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis.
Cell Rep
; 41(12): 111862, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36543129