Detalhe da pesquisa
1.
Glycoengineering of Antibodies for Modulating Functions.
Annu Rev Biochem
; 88: 433-459, 2019 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30917003
2.
Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody.
Proc Natl Acad Sci U S A
; 115(47): 12023-12027, 2018 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30397147
3.
Principal component analysis for automated classification of 2D spectra and interferograms of protein therapeutics: influence of noise, reconstruction details, and data preparation.
J Biomol NMR
; 74(10-11): 643-656, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32700053
4.
Comparative Analysis of One-Dimensional Protein Fingerprint by Line Shape Enhancement and Two-Dimensional 1H,13C Methyl NMR Methods for Characterization of the Higher Order Structure of IgG1 Monoclonal Antibodies.
Anal Chem
; 92(9): 6366-6373, 2020 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32267681
5.
Modulating IgG effector function by Fc glycan engineering.
Proc Natl Acad Sci U S A
; 114(13): 3485-3490, 2017 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28289219
6.
Implementation of Glycan Remodeling to Plant-Made Therapeutic Antibodies.
Int J Mol Sci
; 19(2)2018 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29385073
7.
Glycosynthase Mutants of Endoglycosidase S2 Show Potent Transglycosylation Activity and Remarkably Relaxed Substrate Specificity for Antibody Glycosylation Remodeling.
J Biol Chem
; 291(32): 16508-18, 2016 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27288408
8.
Endo-F3 Glycosynthase Mutants Enable Chemoenzymatic Synthesis of Core-fucosylated Triantennary Complex Type Glycopeptides and Glycoproteins.
J Biol Chem
; 291(17): 9356-70, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26966183
9.
Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies.
Proc Natl Acad Sci U S A
; 111(18): 6714-9, 2014 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24753590
10.
An Fc-Small Molecule Conjugate for Targeted Inhibition of the Adenosineâ 2A Receptor.
Chembiochem
; 17(20): 1951-1960, 2016 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27432157
11.
An Fc domain protein-small molecule conjugate as an enhanced immunomodulator.
J Am Chem Soc
; 136(9): 3370-3, 2014 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24533830
12.
Chemoenzymatic Fc glycosylation via engineered aldehyde tags.
Bioconjug Chem
; 25(4): 788-95, 2014 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24702330
13.
Correlated analytical and functional evaluation of higher order structure perturbations from oxidation of NISTmAb.
MAbs
; 15(1): 2160227, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36683157
14.
Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.
J Am Chem Soc
; 134(29): 12308-18, 2012 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22747414
15.
Ligand-Bound Forced Degradation as a Strategy to Generate Functionally Relevant Analytical Challenge Materials for Assessment of CQAs.
Front Mol Biosci
; 9: 789973, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35480883
16.
Multivalent Antigen Presentation Enhances the Immunogenicity of a Synthetic Three-Component HIV-1 V3 Glycopeptide Vaccine.
ACS Cent Sci
; 4(5): 582-589, 2018 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29806004
17.
Synthetic HIV V3 Glycopeptide Immunogen Carrying a N334 N-Glycan Induces Glycan-Dependent Antibodies with Promiscuous Site Recognition.
J Med Chem
; 61(22): 10116-10125, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30384610
18.
Heterologous recombinant expression of non-originator NISTmAb.
MAbs
; 10(6): 922-933, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29958062
19.
Systematic Synthesis and Binding Study of HIV V3 Glycopeptides Reveal the Fine Epitopes of Several Broadly Neutralizing Antibodies.
ACS Chem Biol
; 12(6): 1566-1575, 2017 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28414420
20.
Synthetic multivalent V3 glycopeptides display enhanced recognition by glycan-dependent HIV-1 broadly neutralizing antibodies.
Chem Commun (Camb)
; 53(39): 5453-5456, 2017 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28466900