Detalhe da pesquisa
1.
Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing.
Cell
; 141(5): 786-98, 2010 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20510926
2.
MET currents and otoacoustic emissions from mice with a detached tectorial membrane indicate the extracellular matrix regulates Ca2+ near stereocilia.
J Physiol
; 599(7): 2015-2036, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33559882
3.
Age-related changes in the biophysical and morphological characteristics of mouse cochlear outer hair cells.
J Physiol
; 598(18): 3891-3910, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32608086
4.
A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane.
Development
; 144(21): 3978-3989, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28935705
5.
Ultrastructural defects in stereocilia and tectorial membrane in aging mouse and human cochleae.
J Neurosci Res
; 98(9): 1745-1763, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31762086
6.
The acquisition of mechano-electrical transducer current adaptation in auditory hair cells requires myosin VI.
J Physiol
; 594(13): 3667-81, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27111754
7.
Three deaf mice: mouse models for TECTA-based human hereditary deafness reveal domain-specific structural phenotypes in the tectorial membrane.
Hum Mol Genet
; 23(10): 2551-68, 2014 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24363064
8.
Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2.
Proc Natl Acad Sci U S A
; 110(34): 13898-903, 2013 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23918390
9.
Loss of the tectorial membrane protein CEACAM16 enhances spontaneous, stimulus-frequency, and transiently evoked otoacoustic emissions.
J Neurosci
; 34(31): 10325-38, 2014 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25080593
10.
A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss.
Am J Hum Genet
; 91(5): 919-27, 2012 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23084290
11.
A mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation.
Proc Natl Acad Sci U S A
; 109(47): 19351-6, 2012 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23129639
12.
Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.
Nature
; 456(7219): 255-8, 2008 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18849963
13.
Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia.
Proc Natl Acad Sci U S A
; 108(14): 5825-30, 2011 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21436032
14.
Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with alpha-tectorin and is mutated in autosomal dominant hearing loss (DFNA4).
Proc Natl Acad Sci U S A
; 108(10): 4218-23, 2011 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21368133
15.
Hair bundle defects and loss of function in the vestibular end organs of mice lacking the receptor-like inositol lipid phosphatase PTPRQ.
J Neurosci
; 32(8): 2762-72, 2012 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22357859
16.
Visualizing Collagen Fibrils in the Cochlea's Tectorial and Basilar Membranes Using a Fluorescently Labeled Collagen-Binding Protein Fragment.
J Assoc Res Otolaryngol
; 24(2): 147-157, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36725777
17.
AAV-mediated rescue of Eps8 expression in vivo restores hair-cell function in a mouse model of recessive deafness.
Mol Ther Methods Clin Dev
; 26: 355-370, 2022 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36034774
18.
Sharpened cochlear tuning in a mouse with a genetically modified tectorial membrane.
Nat Neurosci
; 10(2): 215-23, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17220887
19.
Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity.
JCI Insight
; 6(7)2021 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33735112
20.
Aminoglycoside-induced phosphatidylserine externalization in sensory hair cells is regionally restricted, rapid, and reversible.
J Neurosci
; 28(40): 9939-52, 2008 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18829952