Detalhe da pesquisa
1.
Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerases.
Cell
; 185(17): 3232-3247.e18, 2022 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35952671
2.
Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases.
PLoS Genet
; 18(9): e1010189, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36155972
3.
Fine-mapping inflammatory bowel disease loci to single-variant resolution.
Nature
; 547(7662): 173-178, 2017 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28658209
4.
A comprehensive evaluation of the genetic architecture of sudden cardiac arrest.
Eur Heart J
; 39(44): 3961-3969, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30169657
5.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Nature
; 491(7422): 119-24, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23128233
6.
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.
Lancet
; 387(10014): 156-67, 2016 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26490195
7.
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.
Nat Genet
; 40(9): 1107-12, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19165925
8.
Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis.
PLoS Genet
; 9(9): e1003723, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24068945
9.
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.
Nat Genet
; 39(5): 596-604, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17435756
10.
A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease.
PLoS Genet
; 7(1): e1001283, 2011 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21298027
11.
Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals.
PLoS Genet
; 7(6): e1002158, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21738491
12.
Identifying transcript-level differential expression in primary human immune cells.
Mol Immunol
; 153: 181-193, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36527757
13.
Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases.
Proc Natl Acad Sci U S A
; 106(44): 18680-5, 2009 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19846760
14.
IBD-associated G protein-coupled receptor 65 variant compromises signalling and impairs key functions involved in inflammation.
Cell Signal
; 93: 110294, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35218908
15.
Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation.
Sci Immunol
; 7(70): eabn6660, 2022 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35394816
16.
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.
Nat Genet
; 54(9): 1275-1283, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36038634
17.
Defining the role of the MHC in autoimmunity: a review and pooled analysis.
PLoS Genet
; 4(4): e1000024, 2008 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18437207
18.
Functional screen of inflammatory bowel disease genes reveals key epithelial functions.
Genome Med
; 13(1): 181, 2021 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34758847
19.
A transcriptome-based approach to identify functional modules within and across primary human immune cells.
PLoS One
; 15(5): e0233543, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32469933
20.
Phenotypic and genotypic characteristics of inflammatory bowel disease in French Canadians: comparison with a large North American repository.
Am J Gastroenterol
; 104(9): 2233-40, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19513023