Detalhe da pesquisa
1.
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.
Proc Natl Acad Sci U S A
; 116(10): 4696-4705, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770445
2.
Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
Hum Mol Genet
; 28(15): 2459-2476, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31067307
3.
Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
Hum Mol Genet
; 28(18): 3161-3162, 2019 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31504503
4.
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.
Res Sq
; 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38343852
5.
IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS-associated amyotrophic lateral sclerosis.
Brain Pathol
; 34(1): e13206, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37582053
6.
Increased proliferation and differentiation capacity of placenta-derived mesenchymal stem cells from women of median maternal age correlates with telomere shortening.
Aging (Albany NY)
; 13(22): 24542-24559, 2021 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34845112
7.
XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells.
NAR Cancer
; 2(3): zcaa013, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32776008
8.
RT2 PCR array screening reveals distinct perturbations in DNA damage response signaling in FUS-associated motor neuron disease.
Mol Brain
; 12(1): 103, 2019 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31801573
9.
TDP-43/FUS in motor neuron disease: Complexity and challenges.
Prog Neurobiol
; 145-146: 78-97, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27693252
10.
New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases.
Biomolecules
; 4(3): 678-703, 2014 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25036887