Detalhe da pesquisa
1.
Structural analysis of the P132L disease mutation in caveolin-1 reveals its role in the assembly of oligomeric complexes.
J Biol Chem
; 299(4): 104574, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870682
2.
Probable digenic inheritance of Diamond-Blackfan anemia.
Am J Med Genet A
; 194(3): e63454, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37897121
3.
Undiagnosed Disease Network collaborative approach in diagnosing rare disease in a patient with a mosaic CACNA1D variant.
Am J Med Genet A
; 194(7): e63597, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38511854
4.
Template-free prediction of a new monotopic membrane protein fold and assembly by AlphaFold2.
Biophys J
; 122(11): 2041-2052, 2023 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36352786
5.
Silent agonists for α7 nicotinic acetylcholine receptors.
Pharmacol Res
; 190: 106736, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36940890
6.
Prediction of amphipathic helix-membrane interactions with Rosetta.
PLoS Comput Biol
; 17(3): e1008818, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33730029
7.
Veratridine Can Bind to a Site at the Mouth of the Channel Pore at Human Cardiac Sodium Channel NaV1.5.
Int J Mol Sci
; 23(4)2022 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216338
8.
Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design.
Biochemistry
; 60(11): 825-846, 2021 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33705117
9.
A Computational Analysis of the Factors Governing the Dynamics of α7 nAChR and Its Homologs.
Biophys J
; 119(8): 1656-1669, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33010233
10.
Macroscopic and Microscopic Activation of α7 Nicotinic Acetylcholine Receptors by the Structurally Unrelated Allosteric Agonist-Positive Allosteric Modulators (ago-PAMs) B-973B and GAT107.
Mol Pharmacol
; 95(1): 43-61, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30348894
11.
Allosteric Agonism of α7 Nicotinic Acetylcholine Receptors: Receptor Modulation Outside the Orthosteric Site.
Mol Pharmacol
; 95(6): 606-614, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30944209
12.
The novel non-hallucinogenic compound DM506 (3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole) induces sedative- and anxiolytic-like activity in mice by a mechanism involving 5-HT2A receptor activation.
Eur J Pharmacol
; 966: 176329, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253116
13.
Benchmarking AlphaFold2 on peptide structure prediction.
Structure
; 31(1): 111-119.e2, 2023 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36525975
14.
Molecular architecture of the human caveolin-1 complex.
Sci Adv
; 8(19): eabn7232, 2022 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35544577
15.
The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site.
Toxins (Basel)
; 13(8)2021 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34437426
16.
Nicotinic receptor pharmacology in silico: Insights and challenges.
Neuropharmacology
; 177: 108257, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738311
17.
An Investigation of Three-Finger Toxin-nAChR Interactions through Rosetta Protein Docking.
Toxins (Basel)
; 12(9)2020 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32947868
18.
In Silico Modeling of the α7 Nicotinic Acetylcholine Receptor: New Pharmacological Challenges Associated with Multiple Modes of Signaling.
Mini Rev Med Chem
; 20(10): 841-864, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32000651
19.
Sulfonium as a Surrogate for Ammonium: A New α7 Nicotinic Acetylcholine Receptor Partial Agonist with Desensitizing Activity.
J Med Chem
; 60(18): 7928-7934, 2017 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28885019