Detalhe da pesquisa
1.
Direct, genome-wide assessment of DNA mutations in single cells.
Nucleic Acids Res
; 40(5): 2032-40, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22086961
2.
Hacking hematopoiesis - emerging tools for examining variant effects.
Dis Model Mech
; 16(3)2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36826849
3.
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells.
Nat Cell Biol
; 25(4): 528-539, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37024683
4.
Direct mutation analysis by high-throughput sequencing: from germline to low-abundant, somatic variants.
Mutat Res
; 729(1-2): 1-15, 2012 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22016070
5.
The biomechanics of metaphyseal cone augmentation in revision knee replacement.
J Mech Behav Biomed Mater
; 131: 105233, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35504197
6.
Single-cell damagenome profiling unveils vulnerable genes and functional pathways in human genome toward DNA damage.
Sci Adv
; 7(27)2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34215579
7.
Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities.
Blood Adv
; 5(19): 3876-3890, 2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34492683
8.
It's All About MEis: Menin-MLL Inhibition Eradicates NPM1-Mutated and MLL-Rearranged Acute Leukemias in Mice.
Cancer Cell
; 37(3): 267-269, 2020 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32183947
9.
Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.
Cell Stem Cell
; 27(2): 326-335.e4, 2020 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32673568
10.
Large-scale GMP-compliant CRISPR-Cas9-mediated deletion of the glucocorticoid receptor in multivirus-specific T cells.
Blood Adv
; 4(14): 3357-3367, 2020 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32717029
11.
New insights into the biology of acute myeloid leukemia with mutated NPM1.
Int J Hematol
; 110(2): 150-160, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-30632059
12.
The feasibility of using citizens to segment anatomy from medical images: Accuracy and motivation.
PLoS One
; 14(10): e0222523, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31600225
13.
Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.
J Vis Exp
; (134)2018 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29708546
14.
Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity.
Elife
; 72018 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29570050
15.
Mutant NPM1 Maintains the Leukemic State through HOX Expression.
Cancer Cell
; 34(3): 499-512.e9, 2018 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30205049
16.
DNMT3A in Leukemia.
Cold Spring Harb Perspect Med
; 7(2)2017 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003281
17.
Technical considerations for the use of CRISPR/Cas9 in hematology research.
Exp Hematol
; 54: 4-11, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28757433
18.
DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A.
Genome Biol
; 18(1): 176, 2017 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923089
19.
Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein.
Nat Commun
; 8: 16026, 2017 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28695892
20.
Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.
Cell Rep
; 17(5): 1453-1461, 2016 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27783956