Detalhe da pesquisa
1.
HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells.
Mol Cell
; 77(2): 384-394.e4, 2020 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31806351
2.
ChemRAP uncovers specific mRNA translation regulation via RNA 5' phospho-methylation.
EMBO Rep
; 25(3): 1570-1588, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38263329
3.
Development of Peptide Displacement Assays to Screen for Antagonists of DDB1 Interactions.
Biochemistry
; 63(10): 1297-1306, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38729622
4.
Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation.
Nat Chem Biol
; 18(9): 963-971, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35676539
5.
Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets.
J Chem Inf Model
; 63(13): 4070-4078, 2023 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37350740
6.
HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells.
Mol Cell
; 77(5): 1154, 2020 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32142687
7.
The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface.
Nucleic Acids Res
; 49(20): 11810-11822, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34718722
8.
Identification of lysine isobutyrylation as a new histone modification mark.
Nucleic Acids Res
; 49(1): 177-189, 2021 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33313896
9.
Big data and benchmarking initiatives to bridge the gap from AlphaFold to drug design.
Nat Chem Biol
; 2024 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38459278
10.
Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.
Nucleic Acids Res
; 47(3): 1225-1238, 2019 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30462309
11.
Class I major histocompatibility complex, the trojan horse for secretion of amyloidogenic ß2-microglobulin.
J Biol Chem
; 289(6): 3318-27, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24338476
12.
Probing the CRL4DCAF12 interactions with MAGEA3 and CCT5 di-Glu C-terminal degrons.
PNAS Nexus
; 3(4): pgae153, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38665159
13.
Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing.
Nat Commun
; 15(1): 2809, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38561334
14.
Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials.
J Med Chem
; 67(5): 3467-3503, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38372781
15.
The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition.
Commun Biol
; 6(1): 1272, 2023 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38104184
16.
Discovery of a 53BP1 Small Molecule Antagonist Using a Focused DNA-Encoded Library Screen.
J Med Chem
; 66(20): 14133-14149, 2023 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37782247
17.
Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning.
J Med Chem
; 66(23): 16051-16061, 2023 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37996079
18.
Discovery of Nanomolar DCAF1 Small Molecule Ligands.
J Med Chem
; 66(7): 5041-5060, 2023 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36948210
19.
Structure and Function of Protein Arginine Methyltransferase PRMT7.
Life (Basel)
; 11(8)2021 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34440512
20.
Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2.
Cell Discov
; 7(1): 122, 2021 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34961760