Detalhe da pesquisa
1.
Pharmacokinetics and tolerability of cabotegravir and rilpivirine long-acting intramuscular injections to the vastus lateralis (lateral thigh) muscles of healthy adult participants.
Antimicrob Agents Chemother
; 68(1): e0078123, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38038460
2.
Long-acting cabotegravir pharmacokinetics with and without oral lead-in for HIV PrEP.
Antimicrob Agents Chemother
; : e0147523, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38709006
3.
Expanded Multivariable Models to Assist Patient Selection for Long-Acting Cabotegravir + Rilpivirine Treatment: Clinical Utility of a Combination of Patient, Drug Concentration, and Viral Factors Associated With Virologic Failure.
Clin Infect Dis
; 77(10): 1423-1431, 2023 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37340869
4.
Comparison of Pharmacokinetics of the GalNAc-Conjugated Antisense Oligonucleotide GSK3389404 in Participants with Chronic Hepatitis B Infection across the Asia-Pacific Region.
Antimicrob Agents Chemother
; 67(1): e0090022, 2023 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36507675
5.
Phase IIa, randomised, double-blind study of GSK3389404 in patients with chronic hepatitis B on stable nucleos(t)ide therapy.
J Hepatol
; 77(4): 967-977, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35714812
6.
Safety, Tolerability, Pharmacokinetics, and Acceptability of Oral and Long-Acting Cabotegravir in HIV-Negative Chinese Men.
Antimicrob Agents Chemother
; 66(3): e0205721, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35129374
7.
Multiparametric magnetic resonance imaging to characterize cabotegravir long-acting formulation depot kinetics in healthy adult volunteers.
Br J Clin Pharmacol
; 88(4): 1655-1666, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34240449
8.
Multicompartmental pharmacokinetic evaluation of long-acting cabotegravir in healthy adults for HIV preexposure prophylaxis.
Br J Clin Pharmacol
; 88(4): 1667-1678, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34240467
9.
Population pharmacokinetics of cabotegravir following administration of oral tablet and long-acting intramuscular injection in adult HIV-1-infected and uninfected subjects.
Br J Clin Pharmacol
; 88(10): 4607-4622, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35695476
10.
Randomized clinical trials towards a single-visit cure for chronic hepatitis C: Oral GSK2878175 and injectable RG-101 in chronic hepatitis C patients and long-acting injectable GSK2878175 in healthy participants.
J Viral Hepat
; 27(7): 699-708, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32096313
11.
Reply to Cossu et al., "Switching to deltoid intramuscular injections maintains therapeutic trough concentrations of rilpivirine and cabotegravir in people with HIV".
Antimicrob Agents Chemother
; 68(5): e0020424, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38534102
12.
Modeling and simulation of maintenance treatment in first-line non-small cell lung cancer with external validation.
BMC Cancer
; 16: 473, 2016 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27412292
13.
Bevacizumab dosing strategy in paediatric cancer patients based on population pharmacokinetic analysis with external validation.
Br J Clin Pharmacol
; 81(1): 148-60, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26345283
14.
Lack of a pharmacokinetic interaction between trastuzumab and carboplatin in the presence of docetaxel: results from a phase Ib study in patients with HER2-positive metastatic or locally advanced inoperable solid tumors.
Anticancer Drugs
; 26(4): 448-55, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25643049
15.
Population pharmacokinetics of oseltamivir in non-pregnant and pregnant women.
Br J Clin Pharmacol
; 80(5): 1042-50, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26040405
16.
Sirolimus pharmacokinetics in early postmyeloablative pediatric blood and marrow transplantation.
Biol Blood Marrow Transplant
; 19(4): 569-75, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23266742
17.
Practical dosing guidance for the management of clinician-administered injections of long-acting cabotegravir and rilpivirine.
Ther Adv Infect Dis
; 10: 20499361231214626, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38107552
18.
Preclinical and Phase 1 Assessment of Antisense Oligonucleotide Bepirovirsen in Hepatitis B Virus-Transgenic Mice and Healthy Human Volunteers: Support for Clinical Dose Selection and Evaluation of Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses.
Clin Pharmacol Drug Dev
; 11(10): 1191-1202, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35971951
19.
Pharmacokinetics of oseltamivir among pregnant and nonpregnant women.
Am J Obstet Gynecol
; 204(6 Suppl 1): S84-8, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21492826
20.
Bioavailability and population pharmacokinetics of voriconazole in lung transplant recipients.
Antimicrob Agents Chemother
; 54(10): 4424-31, 2010 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20679503