Detalhe da pesquisa
1.
Interactions between calcium-induced arrhythmia triggers and the electrophysiological-anatomical substrate underlying the induction of atrial fibrillation.
J Physiol
; 602(5): 835-853, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38372694
2.
Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function.
J Biol Chem
; 299(1): 102783, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36502918
3.
Left ventricular noncompaction cardiomyopathy and short QT syndrome due to primary carnitine deficiency.
Ann Noninvasive Electrocardiol
; 28(6): e13077, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37658577
4.
Arrhythmogenic late Ca2+ sparks in failing heart cells and their control by action potential configuration.
Proc Natl Acad Sci U S A
; 117(5): 2687-2692, 2020 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31969455
5.
Inducing Ito,f and phase 1 repolarization of the cardiac action potential with a Kv4.3/KChIP2.1 bicistronic transgene.
J Mol Cell Cardiol
; 164: 29-41, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34823101
6.
Improved Ca2+ release synchrony following selective modification of Itof and phase 1 repolarization in normal and failing ventricular myocytes.
J Mol Cell Cardiol
; 172: 52-62, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35908686
7.
Identification through action potential clamp of proarrhythmic consequences of the short QT syndrome T618I hERG 'hotspot' mutation.
Biochem Biophys Res Commun
; 596: 49-55, 2022 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35114584
8.
Reciprocal interaction between IK1 and If in biological pacemakers: A simulation study.
PLoS Comput Biol
; 17(3): e1008177, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33690622
9.
Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant.
Cell Mol Life Sci
; 78(23): 7899-7914, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34727194
10.
Delayed Ventricular Repolarization and Sodium Channel Current Modification in a Mouse Model of Rett Syndrome.
Int J Mol Sci
; 23(10)2022 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35628543
11.
Identifying locations of re-entrant drivers from patient-specific distribution of fibrosis in the left atrium.
PLoS Comput Biol
; 16(9): e1008086, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32966275
12.
Serine mutation of a conserved threonine in the hERG K+ channel S6-pore region leads to loss-of-function through trafficking impairment.
Biochem Biophys Res Commun
; 526(4): 1085-1091, 2020 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32321643
13.
Late Ca2+ Sparks and Ripples During the Systolic Ca2+ Transient in Heart Muscle Cells.
Circ Res
; 122(3): 473-478, 2018 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29282211
14.
Structure-activity relationship and cardiac safety of 2-aryl-2-(pyridin-2-yl)acetamides as a new class of broad-spectrum anticonvulsants derived from Disopyramide.
Bioorg Chem
; 98: 103717, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32171994
15.
Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence.
Biophys J
; 117(12): 2455-2470, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31451180
16.
Potent hERG channel inhibition by sarizotan, an investigative treatment for Rett Syndrome.
J Mol Cell Cardiol
; 135: 22-30, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31362019
17.
Structural implications of hERG K+ channel block by a high-affinity minimally structured blocker.
J Biol Chem
; 293(18): 7040-7057, 2018 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29545312
18.
Role of SK channel activation in determining the action potential configuration in freshly isolated human atrial myocytes from the SKArF study.
Biochem Biophys Res Commun
; 512(4): 684-690, 2019 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30922569
19.
Mechanistic insight into spontaneous transition from cellular alternans to arrhythmia-A simulation study.
PLoS Comput Biol
; 14(11): e1006594, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30500818
20.
Atrial arrhythmogenicity of KCNJ2 mutations in short QT syndrome: Insights from virtual human atria.
PLoS Comput Biol
; 13(6): e1005593, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28609477