Discussing treatment burden.

Healthcare professionals should help patients to reach informed decisions about treatments in order to maximise benefits while minimising treatment burden https://bit.ly/2XRtRPK.

Patient's treatment burden related to care coordination in the field of respiratory diseases.

The management of respiratory diseases requires various levels of care: multidisciplinary teams, educational and behavioural interventions, self-management and home-based technical support are vital to ensure adequate care management. However, it is often difficult to access these networks due to fragmentation of patient care and treatment burden. Care coordination aims to ensure patients have a central role and that there is continuity of care among various levels and professionals involved. Moreover, the coronavirus disease pandemic has caused strain on the global healthcare system, with care coordination becoming increasingly important in increasing the resilience of health systems, supporting healthcare professionals and ensuring the right treatment and adequate level of care for these patients.

Working for Better Asthma Control: How Can We Improve the Dialogue Between Patients and Healthcare Professionals?

Asthma is a chronic disease affecting more than 300 million people globally. Poor asthma control that leads to unnecessary symptoms is estimated to affect nearly half of people with asthma. A critical way to address poor control is for healthcare professionals (HCPs) and patients to enter a shared dialogue on treatment and asthma management. This article explores the views of both patient and HCP to better understand how to achieve asthma control. From the patient's perspective, being a person with asthma has ramifications to one's sense of identity, and thus one's ability and willingness to actively manage their asthma. Furthermore, lack of education and concerns about the effectiveness of treatment can also ultimately lead to poor control, a term that can be understood differently by patients and HCPs. One goal is to help to normalise life for people with asthma. For this, HCPs need to align on what this means for each individual and then work together to produce a plan that can be applied to the patient's daily life. Training for HCPs on good communication skills and empowering patients to be involved in their asthma management are both critical to ensure effective shared decision-making and, ultimately, improved quality of life for people with asthma. FUNDING: Boehringer Ingelheim. Plain language summary available for this article.

[Individualized treatment of osteoarticular infections in children may shorten the treatment course]. / Individualisering af behandling af osteoartikulære infektioner hos børn kan afkorte behandlingsforløbet.

Older studies have suggested that antibiotic treatment for less than 21 days in children with osteoarticular infections is associated with relapse, and therefore traditionally these infections have been treated for six weeks with an intravenous phase of one week. However, four new prospective studies suggest that if the duration of treatment is individualized and made dependent on the clinical response and the C-reactive protein level, the treatment course may be shortened substantially without increasing the risk of relapse or sequelae. This article reviews older and newer literature on this subject.

Lake restoration by dosing aluminum relative to mobile phosphorus in the sediment.

In the sediment of the shallow, hypertrophic Lake Sønderby, Denmark, potentially mobile phosphorus (Pmobile) was determined by a sequential extraction technique as the sum of porewater P, iron-bound P, and nonreactive P (i.e., polyphosphates and organic P). A good agreement was observed between loss rates of Pmobile in the top 10 cm of the sediment from winter to summer, P release rates measured in undisturbed sediment cores, and rates of P accumulation in the lake water from winter to summer (22, 32, and 30 mg of P m(-2) day(-1), respectively). This suggests that the operationally defined Pmobile was the sediment P fraction responsible for the internal loading in the lake. In autumn 2001, 11 mg of aluminum (Al) L(-1), equivalent to 31 g of Al m(-2), was added to the lake water. This dosage represented a 4:1 molar ratio between Al and Pmobile. The Al treatment significantly decreased lake water P, and P precipitated from the lake water was recovered as Al-bound P in the sediment after the treatment. Internal P loading was reduced by 93% in the two posttreatment years, relative to 2001. Accordingly, average summer concentrations of total P in lake water declined from 1.28 (SE = 0.17) and 1.3 (SE = 0.14) mg L(-1) in the two pretreatment years to 0.09 (SE = 0.01) and 0.13 (SE = 0.01) mg L(-1) in the posttreatment years. pH levels remained unchanged relative to pretreatment levels, while the total alkalinity was reduced from 3.2 (SE = 0.04) to 2.7 (SE = 0.03) mequiv L(-1).