Detalhe da pesquisa
1.
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair.
Nat Cell Biol
; 7(2): 195-201, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15665856
2.
Multivariate evaluation of pharmacological responses in early clinical trials - a study of rIL-21 in the treatment of patients with metastatic melanoma.
Br J Clin Pharmacol
; 69(4): 379-90, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20406222
3.
Clinical and biological efficacy of recombinant human interleukin-21 in patients with stage IV malignant melanoma without prior treatment: a phase IIa trial.
Clin Cancer Res
; 15(6): 2123-9, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19276257
4.
Immune activation in advanced cancer patients treated with recombinant IL-21: multianalyte profiling of serum proteins.
Cancer Immunol Immunother
; 58(6): 843-54, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18925392
5.
Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.
Clin Cancer Res
; 14(17): 5476-83, 2008 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18765539
6.
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.
Mol Cell Biol
; 25(9): 3553-62, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15831461
7.
RAD51 is involved in repair of damage associated with DNA replication in mammalian cells.
J Mol Biol
; 328(3): 521-35, 2003 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12706714
8.
DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer.
Lung Cancer
; 40(2): 157-64, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12711116
9.
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
Int J Cancer
; 105(4): 472-9, 2003 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12712436