Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros

Base de dados
País/Região como assunto
Ano de publicação
Tipo de documento
País de afiliação
Intervalo de ano de publicação
1.
Interact Cardiovasc Thorac Surg ; 12(5): 850-2, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21220414
2.
Interact Cardiovasc Thorac Surg ; 12(5): 744-7, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21172935

RESUMO

The optimal treatment for Masaoka stage IVA thymoma remains controversial. Whilst extrapleural pneumonectomy (EPP) has been proposed, we sought to examine the results of our institutional preference for induction chemotherapy, cytoreductive surgery and intraoperative hyperthermic pleural irrigation. We undertook a retrospective study of patients undergoing surgery for Masaoka stage IVA thymoma following induction chemotherapy over a three-year period at our institution. Between February 2007 and February 2010, 42 patients underwent surgery for thymoma. Six patients underwent surgery with intent to perform cytoreductive surgery and intraoperative hyperthermic pleural irrigation. Complete cytoreductive surgery was not feasible in one patient and thymectomy only was performed. One patient had re-operation for recurrent disease 24 months after the first operation and there were therefore seven procedures undertaken in six patients during the study period. There were no in-hospital deaths. Median follow-up was 18.8 months (range 1.5-31.9 months). One patient died 14 months postoperatively from an acute cardiovascular event. The four remaining patients are alive and well with no evidence of disease recurrence. Multimodality therapy consisting of induction chemotherapy and cytoreductive surgery is a safe, feasible treatment for stage IVA thymoma. Our experience suggest that full pleurectomy is an alternative to EPP.


Assuntos
Hipertermia Induzida , Neoplasias Pleurais/terapia , Irrigação Terapêutica , Toracotomia , Timectomia , Timoma/terapia , Neoplasias do Timo/terapia , Quimioterapia Adjuvante , Feminino , Humanos , Londres , Masculino , Pessoa de Meia-Idade , Terapia Neoadjuvante , Recidiva Local de Neoplasia , Estadiamento de Neoplasias , Cavidade Pleural , Neoplasias Pleurais/secundário , Povidona-Iodo/administração & dosagem , Reoperação , Estudos Retrospectivos , Timoma/secundário , Neoplasias do Timo/patologia , Fatores de Tempo , Resultado do Tratamento
SELEÇÃO DE REFERÊNCIAS
Detalhe da pesquisa