Detalhe da pesquisa
1.
Can upfront DPYD extended variant testing reduce toxicity and associated hospital costs of fluoropyrimidine chemotherapy? A propensity score matched analysis of 2022 UK patients.
BMC Cancer
; 22(1): 458, 2022 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35473510
2.
New indicators and indexes for benchmarking university-industry-government innovation in medical and life science clusters: results from the European FP7 Regions of Knowledge HealthTIES project.
Health Res Policy Syst
; 17(1): 10, 2019 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30691504
3.
A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report.
BMC Cancer
; 16: 629, 2016 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27519597
4.
IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.
Development
; 138(9): 1795-805, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21429986
5.
IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.
BMC Cancer
; 13: 245, 2013 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23688189
6.
Structure and functional analysis of the IGF-II/IGF2R interaction.
EMBO J
; 27(1): 265-76, 2008 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18046459
7.
Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Structure
; 28(12): 1300-1312.e5, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32877646
8.
Structural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11.
Structure
; 15(9): 1065-78, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17850746
9.
Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2rI1565A) results in partial lethality, overgrowth and intestinal adenoma progression.
Sci Rep
; 9(1): 11388, 2019 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31388182
10.
Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting.
Cancer Res
; 66(4): 1940-8, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16488992
11.
Retrospective audit of 957 consecutive 18F-FDG PET-CT scans compared to CT and MRI in 493 patients with different histological subtypes of bone and soft tissue sarcoma.
Clin Sarcoma Res
; 8: 9, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30116519
12.
Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues.
J Mol Biol
; 359(2): 403-21, 2006 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16631789
13.
Epithelial-mesenchymal transition and nuclear ß-catenin induced by conditional intestinal disruption of Cdh1 with Apc is E-cadherin EC1 domain dependent.
Oncotarget
; 7(43): 69883-69902, 2016 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27566565
14.
Durable Response of Spinal Chordoma to Combined Inhibition of IGF-1R and EGFR.
Front Oncol
; 6: 98, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27200287
15.
Diagnostic value of H3F3A mutations in giant cell tumour of bone compared to osteoclast-rich mimics.
J Pathol Clin Res
; 1(2): 113-23, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27499898
16.
Quantification of the heterogeneity of prognostic cellular biomarkers in ewing sarcoma using automated image and random survival forest analysis.
PLoS One
; 9(9): e107105, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25243408
17.
Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype.
PLoS One
; 8(2): e57270, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23468951
18.
Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes.
EMBO Mol Med
; 4(8): 705-18, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22674894
19.
An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science
; 338(6111): 1209-13, 2012 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23197533
20.
Circulating levels of insulin-like growth factor-II/mannose-6-phosphate receptor in obesity and type 2 diabetes.
Growth Horm IGF Res
; 20(3): 185-91, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20110184