Detalhe da pesquisa
1.
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3K-Akt-NF-κB pathway.
Acta Pharmacol Sin
; 45(1): 166-179, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37605050
2.
Sesquiterpenoids and Cytochalasins with Immunosuppressive Activity from Sonchus wightianus.
Chem Biodivers
; 21(4): e202400256, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38361228
3.
Baccaramiones A-D, Four Highly Oxygenated and Rearranged Trinorditerpenoids from Baccaurea ramiflora.
J Org Chem
; 88(1): 455-461, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36516399
4.
Sumatranins A-J: Lignans with Immunosuppressive Activity from Cleistanthus sumatranus.
J Nat Prod
; 86(6): 1606-1614, 2023 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37307145
5.
Dolabrane-Type Diterpenoids with Immunosuppressive Activity from Koilodepas hainanense.
J Nat Prod
; 85(6): 1581-1590, 2022 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35678710
6.
Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms.
Acta Pharmacol Sin
; 43(12): 3055-3061, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36050518
7.
Minor immunosuppressive spiroorthoester group-containing pregnane glycosides from the root barks of Periploca sepium.
Bioorg Chem
; 108: 104641, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33517004
8.
NOD-like receptors in autoimmune diseases.
Acta Pharmacol Sin
; 42(11): 1742-1756, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33589796
9.
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-κB/NLRP3 signaling.
Acta Pharmacol Sin
; 42(4): 593-603, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32747720
10.
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis.
Acta Pharmacol Sin
; 42(10): 1653-1664, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33441995
11.
(-)-Isoscopariusinâ A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis.
Angew Chem Int Ed Engl
; 60(23): 12859-12867, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33620745
12.
Alopecines A-E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides.
Bioorg Chem
; 99: 103812, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32302796
13.
[1,2,4]Triazolo[1,5-a]pyrimidine derivative (Mol-5) is a new NS5-RdRp inhibitor of DENV2 proliferation and DENV2-induced inflammation.
Acta Pharmacol Sin
; 41(5): 706-718, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-31729469
14.
Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-α/IFN-γ-induced inflammatory response in keratinocytes and T cell-derived IL-17.
Pharmacol Res
; 129: 443-452, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29155016
15.
(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcγ receptor signaling.
Acta Pharmacol Sin
; 39(1): 107-116, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28880016
16.
Artemisinin analogue SM934 ameliorates DSS-induced mouse ulcerative colitis via suppressing neutrophils and macrophages.
Acta Pharmacol Sin
; 39(10): 1633-1644, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29849131
17.
(5R)-5-hydroxytriptolide ameliorates lupus nephritis in MRL/lpr mice by preventing infiltration of immune cells.
Am J Physiol Renal Physiol
; 312(4): F769-F777, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28100505
18.
Therapeutic effects of DZ2002, a reversible SAHH inhibitor, on lupus-prone NZB×NZW F1 mice via interference with TLR-mediated APC response.
Acta Pharmacol Sin
; 35(2): 219-29, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24374810
19.
Interplay of IL-17A/IL-17RA signaling with microbial homeostasis in systemic anti-tumoral responses.
MedComm (2020)
; 5(4): e524, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38585232
20.
Limonoids and alkaloids from Tetradium austrosinense (Hand.-Mazz.) T.G.Hartley.
Fitoterapia
; 172: 105759, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38013059