Detalhe da pesquisa
1.
Evaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencing.
Arch Toxicol
; 98(6): 1919-1935, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38584193
2.
Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models.
Arch Toxicol
; 97(10): 2785-2798, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37486449
3.
Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays.
Regul Toxicol Pharmacol
; 141: 105410, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37210026
4.
Key Challenges and Recommendations for In Vitro Testing of Tobacco Products for Regulatory Applications: Consideration of Test Materials and Exposure Parameters.
Altern Lab Anim
; 51(1): 55-79, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36821083
5.
Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s.
Arch Toxicol
; 96(11): 3077-3089, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35882637
6.
Quantitative analysis of the relative mutagenicity of five chemical constituents of tobacco smoke in the mouse lymphoma assay.
Mutagenesis
; 31(3): 287-96, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26001754
7.
Tight junction disruption by cadmium in an in vitro human airway tissue model.
Respir Res
; 16: 30, 2015 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25851441
8.
Continued progress in developing the Pig-a gene mutation assay.
Mutagenesis
; 30(3): 313-4, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25934984
9.
Erythrocyte PIG-A mutant frequencies in cancer patients receiving cisplatin.
Cancer Med
; 13(3): e6895, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38214136
10.
Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT).
Environ Mol Mutagen
; 2024 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38828778
11.
Evaluating the weak in vivo micronucleus response of a genotoxic carcinogen, aristolochic acids.
Mutat Res
; 753(2): 82-92, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23500662
12.
Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT).
Environ Mol Mutagen
; 2023 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37097075
13.
Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting.
Environ Mol Mutagen
; 2023 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38115239
14.
Error-corrected next generation sequencing - Promises and challenges for genotoxicity and cancer risk assessment.
Mutat Res Rev Mutat Res
; 792: 108466, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37643677
15.
In vivo genotoxicity of furan in F344 rats at cancer bioassay doses.
Toxicol Appl Pharmacol
; 261(2): 164-71, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22507866
16.
Genotoxicity of silver nanoparticles evaluated using the Ames test and in vitro micronucleus assay.
Mutat Res
; 745(1-2): 4-10, 2012 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22138422
17.
Genotoxicity of furan in Big Blue rats.
Mutat Res
; 742(1-2): 72-8, 2012 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22200623
18.
90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats.
Food Chem Toxicol
; 160: 112780, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-34965465
19.
Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines.
Mutat Res
; 723(1): 58-64, 2011 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21554981
20.
Manifestation of Pig-a mutant bone marrow erythroids and peripheral blood erythrocytes in mice treated with N-ethyl-N-nitrosourea: direct sequencing of Pig-a cDNA from bone marrow cells negative for GPI-anchored protein expression.
Mutat Res
; 723(1): 36-42, 2011 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21549855