Detalhe da pesquisa
1.
Activity and safety of enobosarm, a novel, oral, selective androgen receptor modulator, in androgen receptor-positive, oestrogen receptor-positive, and HER2-negative advanced breast cancer (Study G200802): a randomised, open-label, multicentre, multinational, parallel design, phase 2 trial.
Lancet Oncol
; 25(3): 317-325, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38342115
2.
Arming androgen receptors to oppose oncogenic estrogen receptor activity in breast cancer.
Br J Cancer
; 125(12): 1599-1601, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34294894
3.
Progesterone receptor modulates ERα action in breast cancer.
Nature
; 523(7560): 313-7, 2015 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26153859
4.
Elevated levels of tumour apolipoprotein D independently predict poor outcome in breast cancer patients.
Histopathology
; 76(7): 976-987, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31994214
5.
Androgen Receptor Signalling Promotes a Luminal Phenotype in Mammary Epithelial Cells.
J Mammary Gland Biol Neoplasia
; 24(1): 99-108, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30099649
6.
Improved relapse-free survival on aromatase inhibitors in breast cancer is associated with interaction between oestrogen receptor-α and progesterone receptor-b.
Br J Cancer
; 119(11): 1316-1325, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30410061
7.
Corrigendum: Progesterone receptor modulates ERα action in breast cancer.
Nature
; 526(7571): 144, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26245370
8.
Hormone-sensing mammary epithelial progenitors: emerging identity and hormonal regulation.
J Mammary Gland Biol Neoplasia
; 20(1-2): 75-91, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26390871
9.
FOXA1: master of steroid receptor function in cancer.
EMBO J
; 30(19): 3885-94, 2011 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21934649
10.
Selective inhibition of CDK9 in triple negative breast cancer.
Oncogene
; 43(3): 202-215, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38001268
11.
The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.
Genome Biol
; 25(1): 44, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38317241
12.
Library size confounds biology in spatial transcriptomics data.
Genome Biol
; 25(1): 99, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38637899
13.
The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer.
Nat Struct Mol Biol
; 31(3): 498-512, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38182927
14.
Designing Fluorescent Nuclear Permeable Peptidomimetics to Target Proliferating Cell Nuclear Antigen.
J Med Chem
; 66(15): 10354-10363, 2023 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37489955
15.
The molecular consequences of androgen activity in the human breast.
Cell Genom
; 3(3): 100272, 2023 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36950379
16.
Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer.
Cancer Res Commun
; 2(7): 706-724, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923279
17.
Corrigendum: Heparanase Promotes Syndecan-1 Expression to Mediate Fibrillar Collagen and Mammographic Density in Human Breast Tissue Cultured ex vivo.
Front Cell Dev Biol
; 9: 678589, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33869234
18.
A cell permeable bimane-constrained PCNA-interacting peptide.
RSC Chem Biol
; 2(5): 1499-1508, 2021 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34704055
19.
High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids.
SLAS Discov
; 26(9): 1107-1124, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34111999
20.
Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer.
Cell Rep
; 34(1): 108585, 2021 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33406413