Detalhe da pesquisa
1.
Design, Synthesis and Anticancer Evaluation of Nitroimidazole Radiosensitisers.
Molecules
; 28(11)2023 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298933
2.
Subcellular Location of Tirapazamine Reduction Dramatically Affects Aerobic but Not Anoxic Cytotoxicity.
Molecules
; 25(21)2020 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33105798
3.
An agent-based model for drug-radiation interactions in the tumour microenvironment: Hypoxia-activated prodrug SN30000 in multicellular tumour spheroids.
PLoS Comput Biol
; 14(10): e1006469, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30356233
4.
Benzotriazine Di-Oxide Prodrugs for Exploiting Hypoxia and Low Extracellular pH in Tumors.
Molecules
; 24(14)2019 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31295864
5.
Efficient Protocol for the Identification of Hypoxic Cell Radiosensitisers.
Adv Exp Med Biol
; 899: 269-90, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27325273
6.
Novel nitroimidazole alkylsulfonamides as hypoxic cell radiosensitisers.
Bioorg Med Chem
; 22(7): 2123-32, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24650701
7.
Hypoxia-directed drug strategies to target the tumor microenvironment.
Adv Exp Med Biol
; 772: 111-45, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24272357
8.
Protein/arabinoxylans gels: effect of mass ratio on the rheological, microstructural and diffusional characteristics.
Int J Mol Sci
; 15(10): 19106-18, 2014 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25338049
9.
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase.
Science
; 379(6636): 996-1003, 2023 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36893255
10.
Separate inputs modulate phosphorylation-dependent and -independent type VI secretion activation.
Mol Microbiol
; 82(5): 1277-90, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22017253
11.
Tissue Pharmacokinetic Properties and Bystander Potential of Hypoxia-Activated Prodrug CP-506 by Agent-Based Modelling.
Front Pharmacol
; 13: 803602, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35211015
12.
Radiosensitisation of SCCVII tumours and normal tissues in mice by the DNA-dependent protein kinase inhibitor AZD7648.
Radiother Oncol
; 166: 162-170, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34861268
13.
Glyoxylate protects against cyanide toxicity through metabolic modulation.
Sci Rep
; 12(1): 4982, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35322094
14.
Helicobacter pylori perceives the quorum-sensing molecule AI-2 as a chemorepellent via the chemoreceptor TlpB.
Microbiology (Reading)
; 157(Pt 9): 2445-2455, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21602215
15.
Misrepresentation of the National Women's Hospital in Auckland, New Zealand.
Am J Public Health
; 106(7): 1208-9, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27285258
16.
Sugar phosphate activation of the stress sensor eIF2B.
Nat Commun
; 12(1): 3440, 2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34103529
17.
Spatially-resolved pharmacokinetic/pharmacodynamic modelling of bystander effects of a nitrochloromethylbenzindoline hypoxia-activated prodrug.
Cancer Chemother Pharmacol
; 88(4): 673-687, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34245333
18.
Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain.
Biochimie
; 183: 100-107, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33476699
19.
Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3.
Pharmaceuticals (Basel)
; 14(12)2021 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34959631
20.
Selectively Targeting Tumor Hypoxia With the Hypoxia-Activated Prodrug CP-506.
Mol Cancer Ther
; 20(12): 2372-2383, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34625504