Detalhe da pesquisa
1.
Conformationally Restricted Glycopeptide Backbone Inhibits Gas-Phase H/D Scrambling between Glycan and Peptide Moieties.
J Am Chem Soc
; 145(44): 23925-23938, 2023 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37883679
2.
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.
Nat Methods
; 16(7): 595-602, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31249422
3.
A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties.
Mol Ther
; 29(5): 1729-1743, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33484965
4.
Investigating the Role of Artemin Glycosylation.
Pharm Res
; 33(6): 1383-98, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908049
5.
RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations.
Cancer Discov
; 13(9): 2012-2031, 2023 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37270847
6.
Post-translational modifications differentially affect IgG1 conformation and receptor binding.
Mol Cell Proteomics
; 9(8): 1716-28, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20103567
7.
Characterization of IgG1 conformation and conformational dynamics by hydrogen/deuterium exchange mass spectrometry.
Anal Chem
; 81(7): 2644-51, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19265386
8.
Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches.
Anal Chem
; 80(19): 7473-81, 2008 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18729476
9.
Influence of glycan modification on IgG1 biochemical and biophysical properties.
J Pharm Biomed Anal
; 151: 133-144, 2018 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29324282
10.
Deciphering the Biophysical Effects of Oxidizing Sulfur-Containing Amino Acids in Interferon-beta-1a using MS and HDX-MS.
J Am Soc Mass Spectrom
; 28(5): 840-849, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28194741
11.
Engineering Aglycosylated IgG Variants with Wild-Type or Improved Binding Affinity to Human Fc Gamma RIIA and Fc Gamma RIIIAs.
J Mol Biol
; 429(16): 2528-2541, 2017 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28694069
12.
Determination of protein oxidation by mass spectrometry and method transfer to quality control.
J Chromatogr A
; 1123(2): 189-98, 2006 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16716331
13.
A comparison of three techniques for quantitative carbohydrate analysis used in characterization of therapeutic antibodies.
Carbohydr Res
; 341(3): 410-9, 2006 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16378604
14.
Utility of Solution X-Ray Scattering for the Development of Antibody Biopharmaceuticals.
J Pharm Sci
; 105(11): 3278-3289, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27637321
15.
Conformational Analysis of Proteins in Highly Concentrated Solutions by Dialysis-Coupled Hydrogen/Deuterium Exchange Mass Spectrometry.
J Am Soc Mass Spectrom
; 27(4): 669-76, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26860088
16.
Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry.
J Pharm Sci
; 105(11): 3269-3277, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27578543
17.
Evaluation of Incremental Siliconization Levels on Soluble Aggregates, Submicron and Subvisible Particles in a Prefilled Syringe Product.
J Pharm Sci
; 105(1): 50-63, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26852839
18.
Technical Decision Making With Higher Order Structure Data: Perspectives on Higher Order Structure Characterization From the Biopharmaceutical Industry.
J Pharm Sci
; 105(12): 3465-3470, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27743675
19.
Technical Decision-Making with Higher Order Structure Data: Detecting Reversible Concentration-Dependent Self-Association in a Monoclonal Antibody and a Preliminary Investigation to Eliminate It.
J Pharm Sci
; 104(11): 3984-3989, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26308556
20.
Characterization of IgG1 Conformation and Conformational Dynamics by Hydrogen/Deuterium Exchange Mass Spectrometry.
Anal Chem
; 81(14): 5966, 2009 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19606834