Detalhe da pesquisa
1.
Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: towards non-invasive glaucoma gene therapy.
Nanomedicine
; 10(8): 1637-47, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24905400
2.
A computational model for overcoming drug resistance using selective dual-inhibitors for aurora kinase A and its T217D variant.
Mol Pharm
; 10(12): 4572-89, 2013 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24094068
3.
Effect of chemical permeation enhancers on stratum corneum barrier lipid organizational structure and interferon alpha permeability.
Mol Pharm
; 10(6): 2248-60, 2013 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23587061
4.
Conformational analysis of the carboxy-terminal tails of human beta-tubulin isotypes.
Biophys J
; 94(6): 1971-82, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17993481
5.
Microtubule assembly of isotypically purified tubulin and its mixtures.
Biophys J
; 95(4): 1993-2008, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18502790
6.
Challenges in neuroprotective nanomedicine development: progress towards noninvasive gene therapy of glaucoma.
Nanomedicine (Lond)
; 7(7): 1067-83, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22846092
7.
Pharmaceutical characterization of solid and dispersed carbon nanotubes as nanoexcipients.
Int J Nanomedicine
; 7: 403-15, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22334774
8.
Computer assisted design of second-generation colchicine derivatives.
Interdiscip Sci
; 2(2): 169-74, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20640786
9.
Discovery and characterization of the laulimalide-microtubule binding mode by mass shift perturbation mapping.
Chem Biol
; 17(7): 725-34, 2010 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20659685
10.
Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity.
J Chem Inf Model
; 49(2): 424-36, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19434843
11.
Free energy calculations on the binding of colchicine and its derivatives with the alpha/beta-tubulin isoforms.
J Chem Inf Model
; 48(9): 1824-32, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18712858
12.
Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing.
J Mol Graph Model
; 27(4): 497-505, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18951052
13.
A unique mode of microtubule stabilization induced by peloruside A.
J Mol Biol
; 378(5): 1016-30, 2008 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-18405918
14.
The roles of beta-tubulin mutations and isotype expression in acquired drug resistance.
Cancer Inform
; 3: 159-81, 2007 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19455242
15.
Direct catalysis of lysine 48-linked polyubiquitin chains by the ubiquitin-activating enzyme.
J Biol Chem
; 282(52): 37454-60, 2007 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17951259
16.
Homology modeling of tubulin: influence predictions for microtubule's biophysical properties.
Eur Biophys J
; 36(1): 35-43, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16941085