Detalhe da pesquisa
1.
Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aß42:Aß40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
J Neurosci
; 40(9): 1956-1974, 2020 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31980586
2.
Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS.
Neurobiol Dis
; 124: 340-352, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30528255
3.
Corrigendum to "Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS" Neurobiology of Disease 124 (2019) 340-352.
Neurobiol Dis
; 132: 104558, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471201
4.
A fluorescent splice-switching mouse model enables high-throughput, sensitive quantification of antisense oligonucleotide delivery and activity.
Cell Rep Methods
; 4(1): 100673, 2024 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38171361
5.
Investigation of the rat model for preclinical evaluation of pH-dependent oral absorption in humans.
Mol Pharm
; 10(11): 3997-4004, 2013 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23961831
6.
Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS.
Cell Death Differ
; 28(3): 915-931, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32994544
7.
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by ß-amyloid pathology.
Neuron
; 109(8): 1283-1301.e6, 2021 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33675684
8.
Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aß.
Alzheimers Res Ther
; 11(1): 97, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31787113
9.
Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's Disease.
J Med Chem
; 60(19): 8083-8102, 2017 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28929759