Detalhe da pesquisa
1.
Structural and functional characterization of a specific antidote for ticagrelor.
Blood
; 125(22): 3484-90, 2015 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25788700
2.
Determination of Human Hepatocyte Intrinsic Clearance for Slowly Metabolized Compounds: Comparison of a Primary Hepatocyte/Stromal Cell Co-culture with Plated Primary Hepatocytes and HepaRG.
Drug Metab Dispos
; 44(4): 527-33, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26851239
3.
HepaRG cells as human-relevant in vitro model to study the effects of inflammatory stimuli on cytochrome P450 isoenzymes.
Drug Metab Dispos
; 43(1): 119-25, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25371393
4.
Primary Human Hepatocyte Spheroid Model as a 3D In Vitro Platform for Metabolism Studies.
J Pharm Sci
; 110(1): 422-431, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33122050
5.
Preclinical Comparison of the Blood-brain barrier Permeability of Osimertinib with Other EGFR TKIs.
Clin Cancer Res
; 27(1): 189-201, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33028591
6.
The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids.
Sci Rep
; 9(1): 11585, 2019 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31406127
7.
Quantification of unbound concentration of ticagrelor in plasma as a proof of mechanism biomarker of the reversal agent, MEDI2452.
PLoS One
; 13(7): e0201202, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30048515
8.
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.
Sci Adv
; 4(6): eaat1719, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29938225
9.
Stapled Vasoactive Intestinal Peptide (VIP) Derivatives Improve VPAC2 Agonism and Glucose-Dependent Insulin Secretion.
ACS Med Chem Lett
; 4(12): 1163-8, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900623