Detalhe da pesquisa
1.
Isolation and Structure Elucidation of JBIR-157, a Skeletally Novel Aromatic Polyketide Produced by the Heterologous Expression of a Cryptic Gene Cluster.
Chem Pharm Bull (Tokyo)
; 72(5): 475-479, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38749722
2.
Collagen Lattice Model, Populated with Heterogeneous Cancer-Associated Fibroblasts, Facilitates Advanced Reconstruction of Pancreatic Cancer Microenvironment.
Int J Mol Sci
; 25(7)2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38612551
3.
Identification of compounds that preferentially suppress the growth of T-cell acute lymphoblastic leukemia-derived cells.
Cancer Sci
; 114(10): 4032-4040, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37522388
4.
LUBAC accelerates B-cell lymphomagenesis by conferring resistance to genotoxic stress on B cells.
Blood
; 136(6): 684-697, 2020 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32325488
5.
New azodyrecins identified by a genome mining-directed reactivity-based screening.
Beilstein J Org Chem
; 18: 1017-1025, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36051562
6.
Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
Cancer Sci
; 112(3): 1225-1234, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33370472
7.
A novel methymycin analog, 12-ketomethymycin N-oxide, produced by the heterologous expression of the large pikromycin/methymycin biosynthetic gene cluster of Streptomyces sp. AM4900.
Biosci Biotechnol Biochem
; 85(4): 890-894, 2021 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33590846
8.
New phenylspirodrimane metabolites MBJ-0030, MBJ-0031, and MBJ-0032 isolated from the soil fungal strain Stachybotrys sp. f23793.
Biosci Biotechnol Biochem
; 84(8): 1570-1575, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32338185
9.
Neothioviridamide, a Polythioamide Compound Produced by Heterologous Expression of a Streptomyces sp. Cryptic RiPP Biosynthetic Gene Cluster.
J Nat Prod
; 81(2): 264-269, 2018 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29381067
10.
Total Synthesis and Structure Determination of JBIR-108-A 2-Hydroxy-2-(1-hydroxyethyl)-2,3-dihydro-3(2H)-furanone Isolated from Streptomyces gramineus IR087Pi-4.
J Org Chem
; 80(1): 114-32, 2015 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25437251
11.
Identification and biosynthesis of new acyloins from the thermophilic bacterium Thermosporothrix hazakensis SK20-1(T).
Chembiochem
; 15(4): 527-32, 2014 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24474719
12.
Notch activator cyclopiazonic acid induces apoptosis in HL-60 cells through calcineurin activation.
J Antibiot (Tokyo)
; 77(1): 30-38, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37938761
13.
Pseudoalteropeptide A, a novel lipopeptide from the marine bacterium Pseudoalteromonas piscicida SWA4_PA4 isolated from marine seaweed.
J Antibiot (Tokyo)
; 74(2): 105-110, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33060815
14.
Phenotypic screening system using three-dimensional (3D) culture models for natural product screening.
J Antibiot (Tokyo)
; 74(10): 660-666, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34326483
15.
Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase.
Sci Rep
; 11(1): 9944, 2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33976244
16.
JBIR-155, a Specific Class D ß-Lactamase Inhibitor of Microbial Origin.
Org Lett
; 23(11): 4415-4419, 2021 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34029112
17.
A novel oxazole-containing tetraene compound, JBIR-159, produced by heterologous expression of the cryptic trans-AT type polyketide synthase biosynthetic gene cluster.
J Antibiot (Tokyo)
; 74(5): 354-358, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33558648
18.
Novel macrolactam compound produced by the heterologous expression of a large cryptic biosynthetic gene cluster of Streptomyces rochei IFO12908.
J Antibiot (Tokyo)
; 73(3): 171-174, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31853031
19.
In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives.
Nat Commun
; 11(1): 4022, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32782248
20.
Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy.
Nat Commun
; 11(1): 4660, 2020 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32938908