Pesquisa | BVS Integralidade em Saúde

1.

A phase 1 trial of NY-ESO-1-specific TCR-engineered T-cell therapy combined with a lymph node-targeting nanoparticulate peptide vaccine for the treatment of advanced soft tissue sarcoma.

Ishihara, Mikiya; Nishida, Yoshihiro; Kitano, Shigehisa; Kawai, Akira; Muraoka, Daisuke; Momose, Fumiyasu; Harada, Naozumi; Miyahara, Yoshihiro; Seo, Naohiro; Hattori, Hiroyoshi; Takada, Kohichi; Emori, Makoto; Kakunaga, Shigeki; Endo, Makoto; Matsumoto, Yoshihiro; Sasada, Tetsuro; Sato, Eiichi; Yamada, Tomomi; Matsumine, Akihiko; Nagata, Yasuhiro; Watanabe, Takashi; Kageyama, Shinichi; Shiku, Hiroshi.

Int J Cancer ; 152(12): 2554-2566, 2023 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-36727538

2.

Prognostic significance of NY-ESO-1 antigen and PIGR expression in esophageal tumors of CHP-NY-ESO-1-vaccinated patients as adjuvant therapy.

Nagata, Yasuhiro; Kageyama, Shinichi; Ishikawa, Takeshi; Kokura, Satoshi; Okayama, Tetsuya; Abe, Tetsuya; Murakami, Masahiko; Otsuka, Koji; Ariyoshi, Tomotake; Kojima, Takashi; Taniguchi, Ken; Kobayashi, Shinichiro; Shimada, Hideaki; Yajima, Satoshi; Suzuki, Takashi; Hirano, Satoshi; Tsuchikawa, Takahiro; Shichinohe, Toshiaki; Ueda, Shugo; Kanetaka, Kengo; Yoneda, Akira; Wada, Hisashi; Doki, Yuichiro; Yamaue, Hiroki; Katsuda, Masahiro; Ohi, Masaki; Yasuda, Hiromi; Kondo, Ken; Kataoka, Masato; Kodera, Yasuhiro; Koike, Masahiko; Shiraishi, Taizo; Miyahara, Yoshihiro; Goshima, Naoki; Fukuda, Eriko; Yamaguchi, Kei; Sato, Eiichi; Ikeda, Hiroaki; Yamada, Tomomi; Osako, Masaharu; Hirai, Kaoru; Miyamoto, Hiroshi; Watanabe, Takashi; Shiku, Hiroshi.

Cancer Immunol Immunother ; 71(11): 2743-2755, 2022 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-35429246

3.

Safety and antibody immune response of CHP-NY-ESO-1 vaccine combined with poly-ICLC in advanced or recurrent esophageal cancer patients.

Ishikawa, Takeshi; Kageyama, Shinichi; Miyahara, Yoshihiro; Okayama, Tetsuya; Kokura, Satoshi; Wang, Linan; Sato, Eiichi; Yagita, Hideo; Itoh, Yoshito; Shiku, Hiroshi.

Cancer Immunol Immunother ; 70(11): 3081-3091, 2021 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-33751208

4.

First-in-human phase I clinical trial of the NY-ESO-1 protein cancer vaccine with NOD2 and TLR9 stimulants in patients with NY-ESO-1-expressing refractory solid tumors.

Ishihara, Mikiya; Tono, Yasutaka; Miyahara, Yoshihiro; Muraoka, Daisuke; Harada, Naozumi; Kageyama, Shinichi; Sasaki, Takeshi; Hori, Yasuhide; Soga, Norihito; Uchida, Katsunori; Shiraishi, Taizo; Sato, Eiichi; Kanda, Hideki; Mizuno, Toshiro; Webster, Gill A; Ikeda, Hiroaki; Katayama, Naoyuki; Sugimura, Yoshiki; Shiku, Hiroshi.

Cancer Immunol Immunother ; 69(4): 663-675, 2020 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-31980914

5.

MAGE-A4, NY-ESO-1 and SAGE mRNA expression rates and co-expression relationships in solid tumours.

Ishihara, Mikiya; Kageyama, Shinichi; Miyahara, Yoshihiro; Ishikawa, Takeshi; Ueda, Shugo; Soga, Norihito; Naota, Hiroaki; Mukai, Katsumi; Harada, Naozumi; Ikeda, Hiroaki; Shiku, Hiroshi.

BMC Cancer ; 20(1): 606, 2020 Jun 29.

Artigo em Inglês | MEDLINE | ID: mdl-32600281

6.

Safety and persistence of WT1-specific T-cell receptor gene-transduced lymphocytes in patients with AML and MDS.

Tawara, Isao; Kageyama, Shinichi; Miyahara, Yoshihiro; Fujiwara, Hiroshi; Nishida, Tetsuya; Akatsuka, Yoshiki; Ikeda, Hiroaki; Tanimoto, Kazushi; Terakura, Seitaro; Murata, Makoto; Inaguma, Yoko; Masuya, Masahiro; Inoue, Naoki; Kidokoro, Tomohide; Okamoto, Sachiko; Tomura, Daisuke; Chono, Hideto; Nukaya, Ikuei; Mineno, Junichi; Naoe, Tomoki; Emi, Nobuhiko; Yasukawa, Masaki; Katayama, Naoyuki; Shiku, Hiroshi.

Blood ; 130(18): 1985-1994, 2017 11 02.

Artigo em Inglês | MEDLINE | ID: mdl-28860210

7.

[Cancer immunotherapy using gene-engineered T cells].

Kageyama, Shinichi.

Rinsho Ketsueki ; 59(2): 216-224, 2018.

Artigo em Japonês | MEDLINE | ID: mdl-29515077

8.

Overcoming regulatory T-cell suppression by a lyophilized preparation of Streptococcus pyogenes.

Hirayama, Michiko; Nishikawa, Hiroyoshi; Nagata, Yasuhiro; Tsuji, Takemasa; Kato, Takuma; Kageyama, Shinichi; Ueda, Shugo; Sugiyama, Daisuke; Hori, Sahoko; Sakaguchi, Shimon; Ritter, Gerd; Old, Lloyd J; Gnjatic, Sacha; Shiku, Hiroshi.

Eur J Immunol ; 43(4): 989-1000, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23436617

9.

Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients.

Kageyama, Shinichi; Wada, Hisashi; Muro, Kei; Niwa, Yasumasa; Ueda, Shugo; Miyata, Hiroshi; Takiguchi, Shuji; Sugino, Sahoko H; Miyahara, Yoshihiro; Ikeda, Hiroaki; Imai, Naoko; Sato, Eiichi; Yamada, Tomomi; Osako, Masaharu; Ohnishi, Mami; Harada, Naozumi; Hishida, Tadashi; Doki, Yuichiro; Shiku, Hiroshi.

J Transl Med ; 11: 246, 2013 Oct 05.

Artigo em Inglês | MEDLINE | ID: mdl-24093426

10.

[A case report of a well-differentiated neuroendocrine tumor in which sunitinib treatment resulted in stable disease].

Tamaru, Satoshi; Mizuno, Toshiro; Oda, Hiroyasu; Sugawara, Yumiko; Saito, Kanako; Yamashita, Yoshiki; Kageyama, Shinichi; Uchida, Katsunori; Imai, Hiroshi; Matsuoka, Nobuyoshi; Katayama, Naoyuki.

Gan To Kagaku Ryoho ; 40(9): 1237-40, 2013 Sep.

Artigo em Japonês | MEDLINE | ID: mdl-24047788

11.

Histological Assessment of Synovial Sarcoma Before and After TCR-T Cell Therapy and Cryoablation: A Case Report.

Asanuma, Kunihiro; Ishihara, Mikiya; Nakamura, Tomoki; Uchida, Katsunori; Hagi, Tomohito; Kageyama, Shinichi; Shiku, Hiroshi; Sudo, Akihiro.

Anticancer Res ; 43(12): 5737-5748, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-38030212

12.

Safety and Efficacy of NY-ESO-1 Antigen-Specific T-Cell Receptor Gene-Transduced T Lymphocytes in Patients with Synovial Sarcoma: A Phase I/II Clinical Trial.

Kawai, Akira; Ishihara, Mikiya; Nakamura, Tomoki; Kitano, Shigehisa; Iwata, Shintaro; Takada, Kohichi; Emori, Makoto; Kato, Koji; Endo, Makoto; Matsumoto, Yoshihiro; Kakunaga, Shigeki; Sato, Eiichi; Miyahara, Yoshihiro; Morino, Kunihiko; Tanaka, Shinya; Takahashi, Shuichi; Matsuo, Fujio; Matsumine, Akihiko; Kageyama, Shinichi; Ueda, Takafumi.

Clin Cancer Res ; 29(24): 5069-5078, 2023 12 15.

Artigo em Inglês | MEDLINE | ID: mdl-37792433

13.

Chimeric antigen receptor T-cell therapy targeting a MAGE A4 peptide and HLA-A*02:01 complex for unresectable advanced or recurrent solid cancer: protocol for a multi-institutional phase 1 clinical trial.

Okumura, Satoshi; Ishihara, Mikiya; Kiyota, Naomi; Yakushijin, Kimikazu; Takada, Kohichi; Kobayashi, Shinichiro; Ikeda, Hiroaki; Endo, Makoto; Kato, Koji; Kitano, Shigehisa; Matsumine, Akihiko; Nagata, Yasuhiro; Kageyama, Shinichi; Shiraishi, Taizo; Yamada, Tomomi; Horibe, Keizo; Takesako, Kazuto; Miwa, Hiroshi; Watanabe, Takashi; Miyahara, Yoshihiro; Shiku, Hiroshi.

BMJ Open ; 12(11): e065109, 2022 Nov 14.

Artigo em Inglês | MEDLINE | ID: mdl-36375974

14.

NY-ESO-1-specific redirected T cells with endogenous TCR knockdown mediate tumor response and cytokine release syndrome.

Ishihara, Mikiya; Kitano, Shigehisa; Kageyama, Shinichi; Miyahara, Yoshihiro; Yamamoto, Noboru; Kato, Hidefumi; Mishima, Hideyuki; Hattori, Hiroyoshi; Funakoshi, Takeru; Kojima, Takashi; Sasada, Tetsuro; Sato, Eiichi; Okamoto, Sachiko; Tomura, Daisuke; Nukaya, Ikuei; Chono, Hideto; Mineno, Junichi; Kairi, Muhammad Faris; Diem Hoang Nguyen, Phuong; Simoni, Yannick; Nardin, Alessandra; Newell, Evan; Fehlings, Michael; Ikeda, Hiroaki; Watanabe, Takashi; Shiku, Hiroshi.

J Immunother Cancer ; 10(6)2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35768164

15.

[Irinotecan as second-line chemotherapy for 5-FU-resistant gastric cancer with disseminated intravascular coagulation: a case report].

Oda, Hiroyasu; Mizuno, Toshiro; Yamashita, Yoshiki; Nomura, Hideki; Saito, Kanako; Tamaru, Satoshi; Kageyama, Shinichi; Katayama, Naoyuki.

Gan To Kagaku Ryoho ; 38(9): 1517-20, 2011 Sep.

Artigo em Japonês | MEDLINE | ID: mdl-21918353

16.

Acute Megakaryoblastic Leukemia Harboring a Subclone Expressing BCR-ABL1 Fusion Gene Product.

Kashima, Emiko; Nakano, Eri; Watanabe, Yasuyuki; Imai, Hiroshi; Oka, Koji; Kageyama, Shinichi; Tanaka, Isao.

Intern Med ; 60(22): 3609-3614, 2021 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-34053988

17.

[Cancer vaccine].

Kageyama, Shinichi.

Nihon Rinsho ; 68(6): 1100-4, 2010 Jun.

Artigo em Japonês | MEDLINE | ID: mdl-20535962

18.

Immunohistochemical expression and clinicopathological assessment of the cancer testis antigens NY-ESO-1 and MAGE-A4 in high-grade soft-tissue sarcoma.

Kakimoto, Takuya; Matsumine, Akihiko; Kageyama, Shinichi; Asanuma, Kunihiro; Matsubara, Takao; Nakamura, Tomoki; Iino, Takahiro; Ikeda, Hiroaki; Shiku, Hiroshi; Sudo, Akihiro.

Oncol Lett ; 17(4): 3937-3943, 2019 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-30881511

19.

Humoral immune responses in patients vaccinated with 1-146 HER2 protein complexed with cholesteryl pullulan nanogel.

Kageyama, Shinichi; Kitano, Shigehisa; Hirayama, Michiko; Nagata, Yasuhiro; Imai, Hiroshi; Shiraishi, Taizo; Akiyoshi, Kazunari; Scott, Andrew M; Murphy, Roger; Hoffman, Eric W; Old, Lloyd J; Katayama, Naoyuki; Shiku, Hiroshi.

Cancer Sci ; 99(3): 601-7, 2008 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-18081877

20.

NY-ESO-1 antigen expression and immune response are associated with poor prognosis in MAGE-A4-vaccinated patients with esophageal or head/neck squamous cell carcinoma.

Ueda, Shugo; Miyahara, Yoshihiro; Nagata, Yasuhiro; Sato, Eiichi; Shiraishi, Taizo; Harada, Naozumi; Ikeda, Hiroaki; Shiku, Hiroshi; Kageyama, Shinichi.

Oncotarget ; 9(89): 35997-36011, 2018 Nov 13.

Artigo em Inglês | MEDLINE | ID: mdl-30542513

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