Detalhe da pesquisa
1.
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer.
Cell
; 184(25): 6119-6137.e26, 2021 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34890551
2.
Sotorasib Is a Pan-RASG12C Inhibitor Capable of Driving Clinical Response in NRASG12C Cancers.
Cancer Discov
; 14(5): 727-736, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38236605
3.
Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer.
Cancer Cell
; 42(3): 413-428.e7, 2024 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38402609
4.
Oncogenic Drivers and Therapeutic Vulnerabilities in KRAS Wild-Type Pancreatic Cancer.
Clin Cancer Res
; 29(22): 4627-4643, 2023 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37463056
5.
A Phase I Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-dose Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma.
Clin Cancer Res
; 29(24): 5047-5056, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37819936
6.
Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.
Cancer Res
; 83(3): 441-455, 2023 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36459568
7.
NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron-Sulfur Cluster Proteins.
Cancer Discov
; 12(9): 2180-2197, 2022 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35771492
8.
Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer.
Cell Metab
; 33(1): 199-210.e8, 2021 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33152323
9.
Differential Outcomes in Codon 12/13 and Codon 61 NRAS-Mutated Cancers in the Phase II NCI-MATCH Trial of Binimetinib in Patients with NRAS-Mutated Tumors.
Clin Cancer Res
; 27(11): 2996-3004, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33637626
10.
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.
Cell Rep
; 35(13): 109291, 2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34192548