Detalhe da pesquisa
1.
Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40.
Bioconjug Chem
; 35(5): 593-603, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38592684
2.
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell
; 134(4): 668-78, 2008 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18724939
3.
Generation of a Porcine Antibody Fab Fragment Using Protein Engineering to Facilitate the Evaluation of Ocular Sustained Delivery Technology.
Mol Pharm
; 19(5): 1540-1547, 2022 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35393854
4.
Retinal and Lens Degeneration in New Zealand White Rabbits Administered Intravitreal TSG-6 Link Domain-Rabbit FAb Fusion Proteins.
Toxicol Pathol
; 49(3): 634-646, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33349160
5.
Tailoring translational strength using Kozak sequence variants improves bispecific antibody assembly and reduces product-related impurities in CHO cells.
Biotechnol Bioeng
; 117(7): 1946-1960, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32246763
6.
In Vivo Stability Profiles of Anti-factor D Molecules Support Long-Acting Delivery Approaches.
Mol Pharm
; 16(1): 86-95, 2019 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30444371
7.
K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody.
Mol Cell
; 39(3): 477-84, 2010 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20655260
8.
Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display.
Proc Natl Acad Sci U S A
; 112(18): 5679-84, 2015 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25902490
9.
In silico selection of therapeutic antibodies for development: viscosity, clearance, and chemical stability.
Proc Natl Acad Sci U S A
; 111(52): 18601-6, 2014 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25512516
10.
Evaluating the Use of Antibody Variable Region (Fv) Charge as a Risk Assessment Tool for Predicting Typical Cynomolgus Monkey Pharmacokinetics.
J Biol Chem
; 290(50): 29732-41, 2015 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26491012
11.
Contribution of Antibody Hydrodynamic Size to Vitreal Clearance Revealed through Rabbit Studies Using a Species-Matched Fab.
Mol Pharm
; 13(9): 2996-3003, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27244474
12.
Solubility Challenges in High Concentration Monoclonal Antibody Formulations: Relationship with Amino Acid Sequence and Intermolecular Interactions.
Mol Pharm
; 12(11): 3896-907, 2015 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26407030
13.
Stability Comparison Between Microglassification and Lyophilization Using a Monoclonal Antibody.
J Pharm Sci
; 113(4): 1054-1060, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863428
14.
Inhibiting alternative pathway complement activation by targeting the factor D exosite.
J Biol Chem
; 287(16): 12886-92, 2012 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22362762
15.
Improved quantitative mass spectrometry methods for characterizing complex ubiquitin signals.
Mol Cell Proteomics
; 10(5): M110.003756, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21048196
16.
Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms.
MAbs
; 14(1): 2135183, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36284469
17.
An Approach to Bioactivity Assessment for Critical Quality Attribute Identification Based on Antibody-Antigen Complex Structure.
J Pharm Sci
; 110(4): 1652-1660, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33383056
18.
Antibody Format and Serum Disposition Govern Ocular Pharmacokinetics of Intravenously Administered Protein Therapeutics.
Front Pharmacol
; 12: 601569, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34025395
19.
Improving therapeutic efficacy of a complement receptor by structure-based affinity maturation.
J Biol Chem
; 284(51): 35605-11, 2009 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19833734
20.
Protein conjugates and fusion proteins as ocular therapeutics.
Drug Discov Today
; 24(8): 1440-1445, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31202674