Detalhe da pesquisa
1.
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis.
Physiol Rev
; 98(3): 1169-1203, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29717933
2.
Dual Deletion of Keap1 and Rbpjκ Genes in Liver Leads to Hepatomegaly and Hypercholesterolemia.
Int J Mol Sci
; 25(9)2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38731931
3.
A Point Mutation at C151 of Keap1 of Mice Abrogates NRF2 Signaling, Cytoprotection in Vitro, and Hepatoprotection in Vivo by Bardoxolone Methyl (CDDO-Me).
Mol Pharmacol
; 104(2): 51-61, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37188495
4.
Forced Hepatic Expression of NRF2 or NQO1 Impedes Hepatocyte Lipid Accumulation in a Lipodystrophy Mouse Model.
Int J Mol Sci
; 24(17)2023 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686150
5.
Novel NRF2-activated cancer treatments utilizing synthetic lethality.
IUBMB Life
; 74(12): 1209-1231, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36200139
6.
Adolescent and early adulthood inflammation-associated dietary patterns in relation to premenopausal mammographic density.
Breast Cancer Res
; 23(1): 71, 2021 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34233736
7.
Genetic or pharmacologic Nrf2 activation increases proteinuria in chronic kidney disease in mice.
Kidney Int
; 99(1): 102-116, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32818518
8.
Biomonitoring of Ambient Outdoor Air Pollutant Exposure in Humans Using Targeted Serum Albumin Adductomics.
Chem Res Toxicol
; 34(4): 1183-1196, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33793228
9.
Serum miR-182 is a predictive biomarker for dichotomization of risk of hepatocellular carcinoma in rats.
Mol Carcinog
; 58(11): 2017-2025, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31373075
10.
Broccoli or Sulforaphane: Is It the Source or Dose That Matters?
Molecules
; 24(19)2019 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31590459
11.
Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo.
Mol Pharmacol
; 93(4): 297-308, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29367259
12.
Nrf2 deletion from adipocytes, but not hepatocytes, potentiates systemic metabolic dysfunction after long-term high-fat diet-induced obesity in mice.
Am J Physiol Endocrinol Metab
; 315(2): E180-E195, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29486138
13.
Profound changes in miRNA expression during cancer initiation by aflatoxin B1 and their abrogation by the chemopreventive triterpenoid CDDO-Im.
Mol Carcinog
; 56(11): 2382-2390, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28218475
14.
Disruption of nuclear factor (erythroid-derived-2)-like 2 antioxidant signaling: a mechanism for impaired activation of stem cells and delayed regeneration of skeletal muscle.
FASEB J
; 30(5): 1865-79, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26839378
15.
KEAP1 and Done? Targeting the NRF2 Pathway with Sulforaphane.
Trends Food Sci Technol
; 69(Pt B): 257-269, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29242678
16.
Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet.
Arch Biochem Biophys
; 591: 57-65, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26701603
17.
NRF2/long noncoding RNA ROR signaling regulates mammary stem cell expansion and protects against estrogen genotoxicity.
J Biol Chem
; 289(45): 31310-8, 2014 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25231996
18.
Keap1/Nrf2 pathway in the frontiers of cancer and non-cancer cell metabolism.
Biochem Soc Trans
; 43(4): 639-44, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26551705
19.
Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase.
J Biol Chem
; 288(35): 25626-25637, 2013 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23878198
20.
The Nrf2 triterpenoid activator, CDDO-imidazolide, protects kidneys from ischemia-reperfusion injury in mice.
Kidney Int
; 85(1): 134-41, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24088953