Detalhe da pesquisa
1.
A Diversifiable Synthetic Platform for the Discovery of New Carbasugar SGLT2 Inhibitors Using Azide-Alkyne Click Chemistry.
Chem Pharm Bull (Tokyo)
; 71(3): 240-249, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36858530
2.
The emerging SARS-CoV-2 papain-like protease: Its relationship with recent coronavirus epidemics.
J Med Virol
; 93(3): 1581-1588, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32902889
3.
Dom34 mediates targeting of exogenous RNA in the antiviral OAS/RNase L pathway.
Nucleic Acids Res
; 47(1): 432-449, 2019 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30395302
4.
Sulfonamide antibiotics inhibit RNAi by binding to human Argonaute protein 2 PAZ.
Bioorg Med Chem Lett
; 30(24): 127637, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33132114
5.
A pilot study on the pharmacokinetics of a single intramuscular injection of cefquinome in Arabian camel calves.
Acta Vet Hung
; 68(1): 59-64, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32384074
6.
Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143.
Cancer Sci
; 109(5): 1455-1467, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-29498789
7.
Synthesis of cationic glucosamino nucleic acids for stabilizing oligonucleotides.
Bioorg Med Chem Lett
; 28(19): 3174-3176, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30170941
8.
Four-and-a-half LIM Domains 1 (FHL1) Protein Interacts with the Rho Guanine Nucleotide Exchange Factor PLEKHG2/FLJ00018 and Regulates Cell Morphogenesis.
J Biol Chem
; 291(48): 25227-25238, 2016 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27765816
9.
Nucleobase azide-ethynylribose click chemistry contributes to stabilizing oligonucleotide duplexes and stem-loop structures.
Bioorg Med Chem Lett
; 27(12): 2655-2658, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28457755
10.
Introduction of 2-O-benzyl abasic nucleosides to the 3'-overhang regions of siRNAs greatly improves nuclease resistance.
Bioorg Med Chem Lett
; 27(24): 5454-5456, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29126849
11.
Reduction-Responsive Guanine Incorporated into G-Quadruplex-Forming DNA.
Chembiochem
; 17(14): 1304-7, 2016 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27124306
12.
Doxifluridine-conjugated 2-5A analog shows strong RNase L activation ability and tumor suppressive effect.
Bioorg Med Chem
; 24(16): 3870-4, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27364610
13.
Threonine 680 phosphorylation of FLJ00018/PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, by epidermal growth factor receptor signaling regulates cell morphology of Neuro-2a cells.
J Biol Chem
; 289(14): 10045-56, 2014 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24554703
14.
Identification of a determinant for strict NADP(H)-specificity and high sensitivity to mixed-type steroid inhibitor of rabbit aldo-keto reductase 1C33 by site-directed mutagenesis.
Arch Biochem Biophys
; 569: 19-25, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25660042
15.
Cloning and characterization of four rabbit aldo-keto reductases featuring broad substrate specificity for xenobiotic and endogenous carbonyl compounds: relationship with multiple forms of drug ketone reductases.
Drug Metab Dispos
; 42(4): 803-12, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24510382
16.
Synthesis of ethynylbenzene-substituted glycol as a versatile probe for labeling oligonucleotides.
Bioorg Med Chem Lett
; 24(6): 1519-22, 2014 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24582478
17.
Synthesis of non-prenyl analogues of baccharin as selective and potent inhibitors for aldo-keto reductase 1C3.
Bioorg Med Chem
; 22(19): 5220-33, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25182963
18.
Chemically modified synthetic microRNA-205 inhibits the growth of melanoma cells in vitro and in vivo.
Mol Ther
; 21(6): 1204-11, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23629002
19.
Probing AKR1C30 and AKR1C31 with site-directed mutagenesis: identifying the roles of residues 54 and 56 in the binding of substrates and inhibitors.
Biol Pharm Bull
; 37(11): 1848-52, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25366490
20.
Synthesis of oligonucleotides with glucosamine at the 3'-position and evaluation of their biological activity.
Bioorg Med Chem Lett
; 23(14): 4157-61, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23743279