Detalhe da pesquisa
1.
Naphthyridinone (NTD) integrase inhibitors 4. Investigating N1 acetamide substituent effects with C3 amide groups.
Bioorg Med Chem Lett
; 24(14): 3104-7, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24908608
2.
Naphthyridinone (NTD) integrase inhibitors: N1 protio and methyl combination substituent effects with C3 amide groups.
Bioorg Med Chem Lett
; 23(2): 422-5, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23245515
3.
Neuromuscular blocking activity and therapeutic potential of mixed-tetrahydroisoquinolinium halofumarates and halosuccinates in rhesus monkeys.
J Med Chem
; 46(12): 2502-15, 2003 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12773054
4.
Novel 4,4-disubstituted piperidine-based C-C chemokine receptor-5 inhibitors with high potency against human immunodeficiency virus-1 and an improved human ether-a-go-go related gene (hERG) profile.
J Med Chem
; 54(11): 3756-67, 2011 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21539377
5.
Synthesis and antiviral activity of 7-benzyl-4-hydroxy-1,5-naphthyridin-2(1H)-one HIV integrase inhibitors.
J Med Chem
; 52(9): 2754-61, 2009 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19374386
6.
Discovery of bioavailable 4,4-disubstituted piperidines as potent ligands of the chemokine receptor 5 and inhibitors of the human immunodeficiency virus-1.
J Med Chem
; 51(20): 6538-46, 2008 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-18811134
7.
The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral.
Antimicrob Agents Chemother
; 52(3): 901-8, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18160521
8.
Synthesis and HIV-integrase strand transfer inhibition activity of 7-hydroxy[1,3]thiazolo[5,4-b]pyridin-5(4H)-ones.
Bioorg Med Chem Lett
; 16(21): 5668-72, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16908139