Detalhe da pesquisa
1.
The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
EMBO J
; 41(20): e110871, 2022 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36059274
2.
Design, synthesis, and evaluation of BCL-2 targeting PROTACs.
Chemistry
; : e202400430, 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38818652
3.
Cereblon enhancer methylation and IMiD resistance in multiple myeloma.
Blood
; 138(18): 1721-1726, 2021 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34115836
4.
Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.
Blood
; 136(26): 3041-3050, 2020 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33367545
5.
Volasertib as a monotherapy or in combination with azacitidine in patients with myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia: summary of three phase I studies.
BMC Cancer
; 22(1): 569, 2022 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35597904
6.
Anti-SARS-CoV2 antibody-mediated cytokine release syndrome in a patient with acute promyelocytic leukemia.
BMC Infect Dis
; 22(1): 537, 2022 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35692034
7.
Making AML fly too close to the sun.
Blood
; 143(15): 1438-1439, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38602697
8.
Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.
Nature
; 523(7559): 183-188, 2015 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26131937
9.
Triggering T-cell activity in CLL.
Blood
; 137(2): 150-151, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33443561
10.
Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia.
Haematologica
; 102(12): 2039-2047, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28971903
11.
Inhibition of Casein Kinase 1 Alpha in Acute Myeloid Leukemia.
N Engl J Med
; 379(19): 1873-1874, 2018 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30403945
12.
Impact of PPM1D mutations in patients with myelodysplastic syndrome and deletion of chromosome 5q.
Am J Hematol
; 96(6): E207-E210, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33725366
13.
Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia.
Blood
; 122(1): 100-8, 2013 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23704090
14.
Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing.
Blood
; 120(18): e83-92, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22976956
15.
High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations.
Blood
; 119(10): e67-75, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22234698
16.
CDK6 protein expression is associated with disease progression and treatment resistance in multiple myeloma.
Hemasphere
; 8(1): e32, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38434534
17.
Heterobifunctional Ligase Recruiters Enable pan-Degradation of Inhibitor of Apoptosis Proteins.
J Med Chem
; 66(7): 4703-4733, 2023 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36996313
18.
Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery.
Nat Commun
; 14(1): 8437, 2023 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38114468
19.
Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design.
RSC Chem Biol
; 4(3): 229-234, 2023 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36908700
20.
Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs.
J Med Chem
; 66(21): 14513-14543, 2023 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37902300