Detalhe da pesquisa
1.
De novo-designed transmembrane proteins bind and regulate a cytokine receptor.
Nat Chem Biol
; 20(6): 751-760, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38480980
2.
Spiers Memorial Lecture: Analysis and de novo design of membrane-interactive peptides.
Faraday Discuss
; 232(0): 9-48, 2021 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34693965
3.
Designed peptides that assemble into cross-α amyloid-like structures.
Nat Chem Biol
; 14(9): 870-875, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061717
4.
Glutamine Side Chain 13Câ18O as a Nonperturbative IR Probe of Amyloid Fibril Hydration and Assembly.
J Am Chem Soc
; 141(18): 7320-7326, 2019 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30998340
5.
Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy.
J Am Chem Soc
; 139(26): 8837-8845, 2017 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28472884
6.
Counting tagged molecules one by one: Quantitative photoactivation and bleaching of photoactivatable fluorophores.
J Chem Phys
; 143(10): 104201, 2015 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26374025
7.
Transient water wires mediate selective proton transport in designed channel proteins.
Nat Chem
; 15(7): 1012-1021, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37308712
8.
Constructing ion channels from water-soluble α-helical barrels.
Nat Chem
; 13(7): 643-650, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972753
9.
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
Res Sq
; 2021 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031651
10.
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Sci Adv
; 7(16)2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33853786
11.
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
bioRxiv
; 2021 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34013269
12.
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation.
bioRxiv
; 2020 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817938
13.
Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
bioRxiv
; 2020 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33269349
14.
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science
; 370(6523): 1473-1479, 2020 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33154106
15.
Synthesis and application of the blue fluorescent amino acid l-4-cyanotryptophan to assess peptide-membrane interactions.
Chem Commun (Camb)
; 55(35): 5095-5098, 2019 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30957824
16.
Solvent-Independent Anharmonicity for Carbonyl Oscillators.
J Phys Chem B
; 121(10): 2331-2338, 2017 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28225620
17.
Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy.
Science
; 353(6303): 1040-1044, 2016 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27701114