Detalhe da pesquisa
1.
Principles and methods for transferring polygenic risk scores across global populations.
Nat Rev Genet
; 25(1): 8-25, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37620596
2.
Improving reporting standards for polygenic scores in risk prediction studies.
Nature
; 591(7849): 211-219, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33692554
3.
Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets.
Am J Hum Genet
; 110(4): 575-591, 2023 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37028392
4.
Prospective, multi-site study of healthcare utilization after actionable monogenic findings from clinical sequencing.
Am J Hum Genet
; 110(11): 1950-1958, 2023 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37883979
5.
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Am J Hum Genet
; 109(8): 1366-1387, 2022 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35931049
6.
Deep generative models of LDLR protein structure to predict variant pathogenicity.
J Lipid Res
; 64(12): 100455, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37821076
7.
Penalized mediation models for multivariate data.
Genet Epidemiol
; 46(1): 32-50, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34664742
8.
Arrhythmia Variant Associations and Reclassifications in the eMERGE-III Sequencing Study.
Circulation
; 145(12): 877-891, 2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34930020
9.
Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups.
Am J Hum Genet
; 106(5): 707-716, 2020 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32386537
10.
Implementing Reporting Standards for Polygenic Risk Scores for Atherosclerotic Cardiovascular Disease.
Curr Atheroscler Rep
; 25(6): 323-330, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37223852
11.
Polygenic scores in biomedical research.
Nat Rev Genet
; 23(9): 524-532, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35354965
12.
Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study.
PLoS Genet
; 16(3): e1008684, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32226016
13.
Multiancestral polygenic risk score for pediatric asthma.
J Allergy Clin Immunol
; 150(5): 1086-1096, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35595084
14.
Transgelin: a new gene involved in LDL endocytosis identified by a genome-wide CRISPR-Cas9 screen.
J Lipid Res
; 63(1): 100160, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34902367
15.
Loci identified by a genome-wide association study of carotid artery stenosis in the eMERGE network.
Genet Epidemiol
; 45(1): 4-15, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32964493
16.
Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid.
Hum Genet
; 141(11): 1739-1748, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35226188
17.
A pragmatic clinical trial of cascade testing for familial hypercholesterolemia.
Genet Med
; 24(12): 2535-2543, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36173399
18.
Pathogenic variants in arteriopathy genes detected in a targeted sequencing study: Penetrance and 1-year outcomes after return of results.
Genet Med
; 24(10): 2123-2133, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35943490
19.
The reckoning: The return of genomic results to 1444 participants across the eMERGE3 Network.
Genet Med
; 24(5): 1130-1138, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216901
20.
Do research participants share genomic screening results with family members?
J Genet Couns
; 31(2): 447-458, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34665896