RESUMO
BACKGROUND: We evaluated the clinical management and risk factors for Trichomonas vaginalis-positive adolescents in upstate South Carolina. METHODS: An Epic electronic medical record report was generated to identify any physician-ordered T. vaginalis test from February 2016 to December 2017 for patients aged 12 to 18 years within the Prisma Health Upstate system. Utilizing a case-control study design of patients with a documented T. vaginalis diagnostic result, we reviewed records of patients with physician-ordered T. vaginalis tests for demographics, clinical disease course, sexually transmitted infection test results, treatment order and dosage, infection risk factors, comorbidities, pregnancy term, and neonatal birth outcomes. RESULTS: Of 789 male and female adolescents with physician-ordered T. vaginalis tests, 44% had a documented result. Of those with a document test result, 13% were T. vaginalis positive. Cases (n = 45) and randomly selected negative controls (n = 45) were all girls. Cases were more likely to be African American, symptomatic, and present with vaginal discharge, pain, and vulvar itch. T. vaginalis patients were more likely to have documented histories of chlamydia (P < 0.0001) and gonorrhea (P = 0.0191), with 18% having concurrent triple infections (T. vaginalis, chlamydia, and gonorrhea). All 26 pregnant girls with T. vaginalis delivered full-term, healthy infants. CONCLUSIONS: We identified a disproportionally high burden of T. vaginalis infection, with an alarmingly high rate of triple infections, among a population of suspected high-risk adolescents. Our results indicate the need to clarify infection prevalence, develop pediatrician-focused education campaigns, and elucidate potentially modifiable risk factors for these high-risk patients.
Assuntos
Vaginite por Trichomonas , Trichomonas vaginalis , Adolescente , Estudos de Casos e Controles , Criança , Feminino , Gonorreia , Humanos , Masculino , Gravidez , Prevalência , Infecções Sexualmente Transmissíveis , Vaginite por Trichomonas/diagnóstico , Vaginite por Trichomonas/epidemiologia , Estados Unidos/epidemiologiaRESUMO
Traditional clinical interventions yield few positive effects on diet. The Healthy Teaching Kitchen (HTK) program implemented by the Veterans Health Administration at sites across the United States delivers interactive nutrition and culinary education, guided instruction, and social opportunities for patients and caregivers. We report HTK outcomes of veterans' self-reported acceptability, self-efficacy for dietary change, and dietary and cooking habits. The HTK program is acceptable and feasible and may empower participants to improve health.
Assuntos
Culinária/métodos , Dieta Saudável/métodos , Promoção da Saúde/organização & administração , Ciências da Nutrição/educação , Saúde dos Veteranos , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estados UnidosRESUMO
OBJECTIVES: Community-associated methicillin-resistant Staphylococcus aureus (MRSA) is a growing problem in the pediatric population, causing many soft tissue infections. This study was designed to examine fingernail carriage of MRSA in children and their caregivers as a possible link to community-associated MRSA soft tissue infections in children. METHODS: We documented the prevalence of MRSA under the fingernails of children and the caregivers of pediatric patients with soft tissue infections and compared the prevalence with MRSA under the fingernails of children and the caregivers of children with no history of soft tissue infections. Children with soft tissue infections and their caregivers (50 subjects) had three fingernails of each hand swabbed and plated and these were compared with a control group of children and their caregivers (150 subjects) who had no history of MRSA or soft tissue infection. RESULTS: Caregivers and children in the study group were more likely than caregivers and the children in the control group to have MRSA under their fingernails (P < 0.05). Soft tissue infections in the study group were found most commonly in the diapering area (66%). CONCLUSIONS: MRSA carriage was evident under the fingernails of children and caregivers. Caregivers and their children who have soft tissue infections are more likely to have MRSA growth under fingernails than caregivers or their children who have no history of MRSA or soft tissue infections. Our study suggests that caregivers could be contributing to soft tissue infections in their children.
Assuntos
Portador Sadio/microbiologia , Infecções Comunitárias Adquiridas/microbiologia , Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Unhas/microbiologia , Infecções dos Tecidos Moles/microbiologia , Infecções Estafilocócicas/microbiologia , Adolescente , Cuidadores , Portador Sadio/epidemiologia , Estudos de Casos e Controles , Criança , Pré-Escolar , Infecções Comunitárias Adquiridas/epidemiologia , Infecções Comunitárias Adquiridas/transmissão , Estudos Transversais , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Prevalência , Infecções dos Tecidos Moles/epidemiologia , Infecções dos Tecidos Moles/transmissão , South Carolina/epidemiologia , Infecções Estafilocócicas/epidemiologia , Infecções Estafilocócicas/transmissãoRESUMO
Health systems and community organizations have increasingly offered nutrition education through teaching kitchens. With an increasing number of older adults (>65 years) accessing these programs, teaching kitchens may consider age-friendly adaptations to their standard curriculum. Based on experiences with implementing Healthy Teaching Kitchens Across Veteran Affairs Health Care System, and by applying the 5M Geriatric Care Framework (Mind, Multicomplexity, Medications, Mobility, What Matters Most), several steps are proposed for teaching kitchens to be able to better accommodate older adults.
Assuntos
Fatores Etários , Culinária , Educação em Saúde/métodos , Ciências da Nutrição/educação , Idoso , Idoso de 80 Anos ou mais , Serviços de Saúde para Idosos , Humanos , Estados Unidos , United States Department of Veterans AffairsRESUMO
Palivizumab is an antirespiratory syncytial virus humanized murine monoclonal antibody that has been shown to reduce the frequency of hospitalization rates of preterm infants infected with respiratory syncytial virus. The United States Food and Drug Administration has approved palivizumab for single-vial dosage; however, if multidose use of single-use vials is proven safe, significant cost savings for respiratory syncytial virus prophylaxis would result. A total of 446 palivizumab vials administered to patients during the respiratory syncytial virus seasons of 2004-2006 were examined for bacterial contamination. One single-use vial showed growth of multiple organisms, and all multidose-use vials were culture negative. The cost benefits of multidose palivizumab vials netted a potential average savings of $37 410 per year in this institution. This study suggests that multidose distribution is a possible solution for cost savings with no increased risk to patients. Secondary to the low incidence of complications, the safety of this practice will require a larger study.
Assuntos
Anticorpos Monoclonais/administração & dosagem , Anticorpos Monoclonais/economia , Antivirais/administração & dosagem , Antivirais/economia , Embalagem de Medicamentos , Anticorpos Monoclonais/efeitos adversos , Anticorpos Monoclonais Humanizados , Antivirais/efeitos adversos , Redução de Custos , Análise Custo-Benefício , Contaminação de Medicamentos/estatística & dados numéricos , Humanos , Lactente , Palivizumab , Infecções por Vírus Respiratório Sincicial/economia , Infecções por Vírus Respiratório Sincicial/prevenção & controle , SegurançaRESUMO
The aim of this study was to examine the viability of methicillin-resistant Staphylococcus aureus (MRSA) in 3 types of swimming pool environments. This study demonstrates that after 1 hour, all MRSA inoculants were found to be nonviable in chlorinated water, saltwater, and biguanide-treated water. This study indicates that swimming pool water that is properly maintained in both public and private swim centers is not likely to be a vehicle to spread MRSA from swimmer to swimmer.
Assuntos
Infecções Comunitárias Adquiridas/microbiologia , Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Viabilidade Microbiana , Piscinas , Microbiologia da Água , Biguanidas/farmacologia , Cloro/farmacologia , Contagem de Colônia Microbiana , Infecções Comunitárias Adquiridas/epidemiologia , Humanos , Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos , Água do Mar/microbiologia , Infecções Estafilocócicas/diagnóstico , Infecções Estafilocócicas/epidemiologiaRESUMO
OBJECTIVES: In Greenville, South Carolina in 1992, erythromycin resistance in GAS was less than 5%, and there were no fully resistant strains. With a large increase in macrolide and azalide usage within the Greenville area, we again examined susceptibility patterns of pharyngeal GAS isolates in 2002 to 2003. METHODS: Community pediatric offices supplied 106 GAS isolates for study. Screening for macrolide resistance was done via Kirby-Bauer disk diffusion testing. Zones of inhibition from 16 to 20 mm were interpreted as intermediately resistant, and those 15 mm or less were interpreted as resistant per National Committee for Clinical Laboratory Standards guidelines. RESULTS: A total of 106 GAS isolates were tested; 0.9% of isolates were intermediately resistant to erythromycin and 11% were fully resistant. CONCLUSIONS: The rate of erythromycin resistance among GAS isolates has increased in the past 10 years in the Greenville community. This pattern has paralleled the increased utilization of macrolides in the same community. Continued monitoring of resistance rates will be needed to alert practitioners of possible treatment failures due to macrolide resistance.