Detalhe da pesquisa
1.
Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes.
Biochem J
; 443(1): 111-23, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22214556
2.
Involvement of inducible 6-phosphofructo-2-kinase in the anti-diabetic effect of peroxisome proliferator-activated receptor gamma activation in mice.
J Biol Chem
; 285(31): 23711-20, 2010 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20498376
3.
Enhancing hepatic glycolysis reduces obesity: differential effects on lipogenesis depend on site of glycolytic modulation.
Cell Metab
; 2(2): 131-40, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16098830
4.
A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.
Biochem J
; 411(1): 41-51, 2008 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18039179
5.
Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes.
Diabetes
; 54(7): 1949-57, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15983194
6.
Roles for fructose-2,6-bisphosphate in the control of fuel metabolism: beyond its allosteric effects on glycolytic and gluconeogenic enzymes.
Adv Enzyme Regul
; 46: 72-88, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16860376
7.
Interaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) with glucokinase activates glucose phosphorylation and glucose metabolism in insulin-producing cells.
Diabetes
; 53(4): 1020-9, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15047617
8.
Reduction of hepatic glucose production as a therapeutic target in the treatment of diabetes.
Curr Drug Targets Immune Endocr Metabol Disord
; 5(1): 51-9, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15777204
9.
A potential role for fructose-2,6-bisphosphate in the stimulation of hepatic glucokinase gene expression.
Endocrinology
; 145(2): 650-8, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14617577
10.
Regulation of glycolysis-role of insulin.
Exp Gerontol
; 40(11): 894-9, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16157461
11.
Regulation of the regulatory enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
Adv Enzyme Regul
; 44: 123-54, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15581487
12.
Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
Am J Physiol Regul Integr Comp Physiol
; 294(3): R766-74, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18199594
13.
Cardiac phosphatase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase increases glycolysis, hypertrophy, and myocyte resistance to hypoxia.
Am J Physiol Heart Circ Physiol
; 294(6): H2889-97, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18456722
14.
Contributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the elevated glycolysis in hepatocytes from Zucker fa/fa rats.
Am J Physiol Regul Integr Comp Physiol
; 293(2): R618-25, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17553851
15.
The promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions.
Am J Physiol Endocrinol Metab
; 292(3): E788-801, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17106062
16.
Cell biology assessment of glucokinase mutations V62M and G72R in pancreatic beta-cells: evidence for cellular instability of catalytic activity.
Diabetes
; 56(7): 1773-82, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17389332
17.
Perturbation of glucose flux in the liver by decreasing F26P2 levels causes hepatic insulin resistance and hyperglycemia.
Am J Physiol Endocrinol Metab
; 291(3): E536-43, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16621898
18.
Investigation of in vivo fatty acid metabolism in AFABP/aP2(-/-) mice.
Am J Physiol Endocrinol Metab
; 288(1): E187-93, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15367400
19.
Identification and characterization of the ATP-binding site in human pancreatic glucokinase.
Arch Biochem Biophys
; 436(1): 23-31, 2005 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15752705
20.
Cre recombinase-dependent expression of a constitutively active mutant allele of the catalytic subunit of protein kinase A.
Genesis
; 43(3): 109-19, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16155866