Detalhe da pesquisa
1.
Fast-Killing Tyrosine Amide ((S)-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus (PfCARL).
ACS Infect Dis
; 9(3): 527-539, 2023 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36763526
2.
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum.
J Med Chem
; 64(5): 2739-2761, 2021 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33620219
3.
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series.
J Med Chem
; 64(9): 6085-6136, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33876936
4.
Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265.
ACS Infect Dis
; 5(1): 90-101, 2019 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30375858
5.
BON-BONs: cyclic molecules with a boron-oxygen-nitrogen backbone. Computational studies of their thermodynamic properties.
J Mol Model
; 18(4): 1661-6, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21811776
6.
Introducing NOB-NOBs: nitrogen-oxygen-boron cycles with potential high-energy properties.
J Mol Model
; 18(5): 1723-8, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21833826