Detalhe da pesquisa
1.
An integrated assessment of the 1,4-dioxane cancer mode of action and threshold response in rodents.
Regul Toxicol Pharmacol
; 142: 105428, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37277058
2.
Characterization of dermal sensitization potential for industrial or agricultural chemicals with EpiSensA.
J Appl Toxicol
; 41(6): 915-927, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33124094
3.
Investigation of potential early key events and mode of action for 1,2-dichloroethane-induced mammary tumors in female rats.
J Appl Toxicol
; 41(3): 362-374, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32830330
4.
Minimum datasets to establish a CAR-mediated mode of action for rodent liver tumors.
Regul Toxicol Pharmacol
; 96: 106-120, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29673940
5.
Dose-Response for Multiple Biomarkers of Exposure and Genotoxic Effect Following Repeated Treatment of Rats with the Alkylating Agents, MMS and MNU.
Mutagenesis
; 31(3): 297-308, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26040483
6.
Mode of action and human relevance of pronamide-induced rat thyroid tumors.
Regul Toxicol Pharmacol
; 71(3): 541-51, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25707858
7.
Pronamide: Human relevance of liver-mediated rat leydig cell tumors.
Regul Toxicol Pharmacol
; 72(2): 394-404, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25846364
8.
A novel approach for concurrent quantitation of glutathione, glutathione disulfide, and 2-hydroxyethylated glutathione in lungs of mice exposed to ethylene oxide, using liquid chromatography-positive electrospray tandem mass spectrometry.
Biomed Chromatogr
; 29(9): 1364-74, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25641649
9.
A critical assessment of the methodologies to investigate the role of inhibition of apoptosis in rodent hepatocarcinogenesis.
Toxicol Mech Methods
; 25(3): 192-200, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25608721
10.
Human relevance framework for rodent liver tumors induced by the insecticide sulfoxaflor.
Crit Rev Toxicol
; 44 Suppl 2: 15-24, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24832551
11.
Mode-of-action and human relevance framework analysis for rat Leydig cell tumors associated with sulfoxaflor.
Crit Rev Toxicol
; 44 Suppl 2: 25-44, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24832552
12.
Key learnings from performance of the U.S. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 in vitro assays.
Birth Defects Res B Dev Reprod Toxicol
; 101(1): 23-42, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24515815
13.
Relevance weighting of tier 1 endocrine screening endpoints by rank order.
Birth Defects Res B Dev Reprod Toxicol
; 101(1): 90-113, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24510745
14.
An integrated approach for prospectively investigating a mode-of-action for rodent liver effects.
Toxicol Appl Pharmacol
; 270(2): 164-73, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23607986
15.
Chlorpyrifos: weight of evidence evaluation of potential interaction with the estrogen, androgen, or thyroid pathways.
Regul Toxicol Pharmacol
; 66(3): 249-63, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23524272
16.
In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (IWGT).
Environ Mol Mutagen
; 2023 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37942839
17.
Epigenetic screening in product safety assessment: are we there yet?
Toxicol Mech Methods
; 21(4): 298-311, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21495868
18.
Assessment of cellular and molecular metrics for dose selection in an in vivo comet assay: A case study with MDI.
Environ Mol Mutagen
; 62(8): 446-457, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34369617
19.
Bridging Sex-Specific Differences in the CAR-Mediated Hepatocarcinogenesis of Nitrapyrin Using Molecular and Apical Endpoints.
Front Toxicol
; 3: 766196, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35295143
20.
Epigenetics and chemical safety assessment.
Mutat Res
; 705(2): 83-95, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20399890