Detalhe da pesquisa
1.
Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice.
Cell
; 185(4): 641-653.e17, 2022 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35123651
2.
Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.
Immunity
; 51(5): 915-929.e7, 2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31732167
3.
Membrane Env Liposomes Facilitate Immunization with Multivalent Full-Length HIV Spikes.
J Virol
; 95(13): e0000521, 2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33883221
4.
Functional Optimization of Broadly Neutralizing HIV-1 Antibody 10E8 by Promotion of Membrane Interactions.
J Virol
; 92(8)2018 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29386285
5.
Functional Stability of HIV-1 Envelope Trimer Affects Accessibility to Broadly Neutralizing Antibodies at Its Apex.
J Virol
; 91(24)2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28978711
6.
Dense Array of Spikes on HIV-1 Virion Particles.
J Virol
; 91(14)2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28446665
7.
Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes.
J Virol
; 89(13): 6725-45, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25878116
8.
Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization.
PLoS Pathog
; 10(7): e1004271, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25058619
9.
Increased functional stability and homogeneity of viral envelope spikes through directed evolution.
PLoS Pathog
; 9(2): e1003184, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23468626
10.
Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions.
Proc Natl Acad Sci U S A
; 107(4): 1529-34, 2010 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20080706
11.
A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin.
Mol Ther Methods Clin Dev
; 28: 366-384, 2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36879849
12.
In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1.
J Virol
; 84(7): 3382-95, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20089658
13.
A low-molecular-weight entry inhibitor of both CCR5- and CXCR4-tropic strains of human immunodeficiency virus type 1 targets a novel site on gp41.
J Virol
; 84(14): 7288-99, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20427524
14.
Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile.
iScience
; 24(9): 102987, 2021 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34505005
15.
Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments.
Cell Rep
; 32(7): 108037, 2020 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814041
16.
An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun
; 10(1): 5389, 2019 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31772165
17.
Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun
; 6: 8167, 2015 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26404402
18.
Prime-boost immunization of rabbits with HIV-1 gp120 elicits potent neutralization activity against a primary viral isolate.
PLoS One
; 8(1): e52732, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23326351
19.
Targeting HIV-1 gp41 in close proximity to the membrane using antibody and other molecules.
Curr Top Med Chem
; 11(24): 2997-3021, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22044228
20.
Functional stability of unliganded envelope glycoprotein spikes among isolates of human immunodeficiency virus type 1 (HIV-1).
PLoS One
; 6(6): e21339, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21738637