Detalhe da pesquisa
1.
Activated EGFR and PDGFR internalize in separate vesicles and downstream AKT and ERK1/2 signaling are differentially impacted by cholesterol depletion.
Biochem Biophys Res Commun
; 665: 195-201, 2023 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37163940
2.
Deubiquitinating enzymes USP4 and USP17 finetune the trafficking of PDGFRß and affect PDGF-BB-induced STAT3 signalling.
Cell Mol Life Sci
; 79(2): 85, 2022 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35064336
3.
The E3 Ubiquitin Ligase TRIM21 Regulates Basal Levels of PDGFRß.
Int J Mol Sci
; 24(9)2023 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175489
4.
Dynamin inhibitors impair platelet-derived growth factor ß-receptor dimerization and signaling.
Exp Cell Res
; 380(1): 69-79, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30970237
5.
Structure-based discovery of novel small molecule inhibitors of platelet-derived growth factor-B.
Bioorg Chem
; 94: 103374, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699389
6.
Stem cell factor receptor/c-Kit: from basic science to clinical implications.
Physiol Rev
; 92(4): 1619-49, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23073628
7.
Dual specificity phosphatase (DUSP)-4 is induced by platelet-derived growth factor -BB in an Erk1/2-, STAT3- and p53-dependent manner.
Biochem Biophys Res Commun
; 519(3): 469-474, 2019 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31526568
8.
The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor ß (PDGFRß) Internalization and Signaling.
J Biol Chem
; 291(22): 11608-18, 2016 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27048651
9.
RhoD binds the Rab5 effector Rabankyrin-5 and has a role in trafficking of the platelet-derived growth factor receptor.
Traffic
; 14(12): 1242-54, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24102721
10.
FGF2 as a potential prognostic biomarker for proneural glioma patients.
Acta Oncol
; 54(3): 385-94, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25263081
11.
The Fer tyrosine kinase is important for platelet-derived growth factor-BB-induced signal transducer and activator of transcription 3 (STAT3) protein phosphorylation, colony formation in soft agar, and tumor growth in vivo.
J Biol Chem
; 288(22): 15736-44, 2013 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23589302
12.
PTPN6 expression is epigenetically regulated and influences survival and response to chemotherapy in high-grade gliomas.
Tumour Biol
; 35(5): 4479-88, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24510345
13.
Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D.
J Steroid Biochem Mol Biol
; 240: 106497, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460707
14.
Platelet-derived growth factor-induced Akt phosphorylation requires mTOR/Rictor and phospholipase C-γ1, whereas S6 phosphorylation depends on mTOR/Raptor and phospholipase D.
Cell Commun Signal
; 11(1): 3, 2013 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23311350
15.
PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets.
Proc Natl Acad Sci U S A
; 107(27): 12216-21, 2010 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20566880
16.
SUMOylation of PDGF receptor α affects signaling via PLCγ and STAT3, and cell proliferation.
BMC Mol Cell Biol
; 24(1): 19, 2023 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37193980
17.
Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression.
Cell Commun Signal
; 10(1): 19, 2012 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22784513
18.
Expression of EGFR and LRIG proteins in oesophageal carcinoma with emphasis on patient survival and cellular chemosensitivity.
Acta Oncol
; 51(1): 69-76, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21417672
19.
VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis.
Proc Natl Acad Sci U S A
; 106(15): 6152-7, 2009 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19369214
20.
Differential impact of lipid raft depletion on platelet-derived growth factor (PDGF)-induced ERK1/2 MAP-kinase, SRC and AKT signaling.
Cell Signal
; 96: 110356, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35605761