Detalhe da pesquisa
1.
Analogs of Marinopyrrole A Show Enhancement to Observed In Vitro Potency against Acute Toxoplasma gondii Infection.
Antimicrob Agents Chemother
; 66(1): e0079421, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34662196
2.
Assessment of Tissue Distribution and Metabolism of MP1, a Novel Pyrrolomycin, in Mice Using a Validated LC-MS/MS Method.
Molecules
; 25(24)2020 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33322110
3.
Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus.
BMC Cancer
; 19(1): 837, 2019 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31455317
4.
Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061280
5.
Marinopyrroles: Unique Drug Discoveries Based on Marine Natural Products.
Med Res Rev
; 36(1): 169-89, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26332654
6.
Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (III).
Mar Drugs
; 12(5): 2458-70, 2014 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24796304
7.
Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim.
Mar Drugs
; 12(3): 1335-48, 2014 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24608970
8.
Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim.
Mar Drugs
; 12(8): 4311-25, 2014 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25076060
9.
Marinopyrrole derivative MP1 as a novel anti-cancer agent in group 3 MYC-amplified Medulloblastoma.
J Exp Clin Cancer Res
; 43(1): 18, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38200580
10.
Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation.
J Biol Chem
; 287(13): 10224-10235, 2012 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22311987
11.
Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (II).
Mar Drugs
; 11(8): 2927-48, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23955285
12.
Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (I).
Mar Drugs
; 10(4): 953-962, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22690153
13.
Natural Product-Based Drug Discovery.
Med Res Rev
; 36(1): 3, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26662060
14.
Total synthesis of (+/-)-marinopyrrole A and its library as potential antibiotic and anticancer agents.
J Comb Chem
; 12(4): 541-7, 2010 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20429575
15.
Drugs for the Treatment of Zika Virus Infection.
J Med Chem
; 63(2): 470-489, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31549836
16.
Enamine Catalytic Annulation of Azonaphthalenes: An Access to Indole Derivatives.
Org Lett
; 21(16): 6557-6561, 2019 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31353910
17.
Kinase and Histone Deacetylase Hybrid Inhibitors for Cancer Therapy.
J Med Chem
; 62(7): 3171-3183, 2019 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30418766
18.
Remote Stereocontrolled Construction of Vicinal Axially Chiral Tetrasubstituted Allenes and Heteroatom-Functionalized Quaternary Carbon Stereocenters.
Org Lett
; 21(2): 503-507, 2019 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30618261
19.
Design, synthesis, cytoselective toxicity, structure-activity relationships, and pharmacophore of thiazolidinone derivatives targeting drug-resistant lung cancer cells.
J Med Chem
; 51(5): 1242-51, 2008 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18257542
20.
Design and synthesis of human immunodeficiency virus entry inhibitors: sulfonamide as an isostere for the alpha-ketoamide group.
J Med Chem
; 50(26): 6535-44, 2007 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18052117