Detalhe da pesquisa
1.
The new N2, N4-diphenylpyridine-2,4-diamine deuterated derivatives as EGFR inhibitors to overcome C797S-mediated resistance.
Bioorg Chem
; 146: 107313, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38554675
2.
Synthesis and evaluation of sulfonamide derivatives targeting EGFR790M/L858R mutations and ALK rearrangement as anticancer agents.
Bioorg Med Chem
; 85: 117241, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37087886
3.
Discovery of potent and effective inhibitors containing sulfoxide structures targeting EML4-ALK rearrangement and EGFR mutant non-small cell lung cancer.
Bioorg Chem
; 138: 106653, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37302317
4.
A Sulfur-Bridging Sulfonate-Modified Zinc(II) Phthalocyanine Nanoliposome Possessing Hybrid Type I and Type II Photoreactions with Efficient Photodynamic Anticancer Effects.
Molecules
; 28(5)2023 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36903498
5.
Discovery of a potent EGFR and ALK dual mutation inhibitor containing N-(3-((4-((2-(cyclopropylsulfinyl)phenyl)amino)pyrimidin-2-yl)amino) phenyl)acrylamide scaffold.
Bioorg Chem
; 129: 106188, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36220003
6.
Novel third-generation pyrimidines-based EGFR tyrosine kinase inhibitors targeting EGFR T790M mutation in advanced non-small cell lung cancer.
Bioorg Chem
; 122: 105743, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35313239
7.
Design, Synthesis, and Evaluation of New Mesenchymal-Epithelial Transition Factor (c-Met) Kinase Inhibitors with Dual Chiral Centers.
Molecules
; 27(17)2022 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36080127
8.
Nanostructured Phthalocyanine Assemblies with Efficient Synergistic Effect of Type I Photoreaction and Photothermal Action to Overcome Tumor Hypoxia in Photodynamic Therapy.
J Am Chem Soc
; 143(34): 13980-13989, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34425676
9.
Synthesis and evaluation of novel 2,4-diaminopyrimidines bearing a sulfoxide moiety as anaplastic lymphoma kinase (ALK) inhibition agents.
Bioorg Med Chem Lett
; 48: 128253, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34245852
10.
Noncovalent Indocyanine Green Conjugate of C-Phycocyanin: Preparation and Tumor-Associated Macrophages-Targeted Photothermal Therapeutics.
Bioconjug Chem
; 31(5): 1438-1448, 2020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32255337
11.
A non-aggregated silicon(IV) phthalocyanine-lactose conjugate for photodynamic therapy.
Bioorg Med Chem Lett
; 30(12): 127164, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32291134
12.
Supramolecular Phthalocyanine Assemblies for Improved Photoacoustic Imaging and Photothermal Therapy.
Angew Chem Int Ed Engl
; 59(22): 8630-8634, 2020 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32077201
13.
A Supramolecular-Based Dual-Wavelength Phototherapeutic Agent with Broad-Spectrum Antimicrobial Activity Against Drug-Resistant Bacteria.
Angew Chem Int Ed Engl
; 59(9): 3658-3664, 2020 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31868285
14.
In Vivo Albumin Traps Photosensitizer Monomers from Self-Assembled Phthalocyanine Nanovesicles: A Facile and Switchable Theranostic Approach.
J Am Chem Soc
; 141(3): 1366-1372, 2019 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30565924
15.
Dual functional cholinesterase and PDE4D inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of tacrine-pyrazolo[3,4-b]pyridine hybrids.
Bioorg Med Chem Lett
; 29(16): 2150-2152, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31281020
16.
Supramolecular photosensitizers rejuvenate photodynamic therapy.
Chem Soc Rev
; 47(4): 1174-1188, 2018 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29334090
17.
Synthesis, Evaluation, and Mechanism Study of New Tepotinib Derivatives as Antiproliferative Agents.
Molecules
; 24(6)2019 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30934578
18.
Evaluation of 4-phenylamino-substituted naphthalene-1,2-diones as tubulin polymerization inhibitors.
Bioorg Med Chem Lett
; 28(18): 3057-3063, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30093295
19.
Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
Bioorg Med Chem Lett
; 28(10): 1769-1775, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29673981
20.
The design, synthesis and evaluation of selenium-containing 4-anilinoquinazoline hybrids as anticancer agents and a study of their mechanism.
Org Biomol Chem
; 16(25): 4701-4714, 2018 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29900452